Science

Hello all.  Genetic testing and full genome sequencing is pretty "affordable" now, and the race to the $1,000 genome seems to be news from 10 years ago now. 

Most of the endless thrashing of utilizing gene expression notions begins with marginal information technology.

Since the NGEN machines squirt out sequences with ease, somewhat without much human dinking as they zoom along, it looks like there is some utility in this alone.

[1] But, there isn't much. The notion: "All the facts are a big linear numbered vector. We just poke em all into memory and some program crawls along and figures things out". Is mostly a failure.

[2] Like pretending a big robot dribbling out magic sauce onto a defective cell from a Cancer patient, proves anything. The HeLa failure of utility thing in full bloom.

[3] The Meta data of genomics and epigenomics, is not ancillary, like the happy talk on the back of the cereal box, versus the stuff in the bowl. The metadata ramps up continuously as other things are figured out. But that's mostly lost, in little plan [1] above.

[4] If want to make DIY Dragons, you need stand alone bills of material of new dragon parts in some manageable form. Not 300 'folders' each with 15 files of 10 different kinds. Knitted together by an utterly untested, one of, unreliable program by a grad student hoping for a PHD. Then 3000 random fullish FASTA's of reptiles. Then:

                                         "Now what ?"; is the big big, problem