Re: [DIYbio] Re: periodontosis


Recently in the general news is this dental-related headline which can be backtracked to the university papers below. 

http://www.bbc.co.uk/news/health-19435442

Coconut oil could combat tooth decay


As usual, journalists fail to link directly to the papers summarized, so some searching is required.  Also not to start on a rant neo-hippie about corporate-institutionalized-medicine america disregarding simple (perhaps non-patentable) solutions for complex treatments but I would bet a sugar cube that dentists prefer cancer-promoting and gum-deteriorating fluoride toothpastes & treatments to those basics mentioned below.   BTW some people enjoy brushing their teeth with Dr Bronners liquid soap which is a coconut-oil based soap ( www.drbronner.com )

First article:

-- quote --

Efficacy of sodium hypochlorite and coconut soap used as disinfecting agents in the reduction of denture stomatitis, Streptococcus mutans and Candida albicans

  1. W. Barnabé1,2,
  2. T. de Mendonça Neto1,
  3. F. C. Pimenta3,
  4. L. F. Pegoraro1,
  5. J. M. Scolaro1

Article first published online: 5 MAY 2004

DOI: 10.1111/j.1365-2842.2004.01254.x

summary This study evaluated the reduction of denture stomatitis and the antimicrobial activity of 0·05% sodium hypochlorite opposed to Candida albicans and Streptococcus mutans (SGM) when associated with brushing complete dentures with coconut soap. The mucosal characteristics were evaluated according to Newton's classification at baseline, after cleansing the dentures with coconut soap for 15 days in group 1 (nine patients). In the other group (19 patients) the analysis were made before and after cleansing the dentures with coconut soap and with disinfection in a soak solution of 0·05% sodium hypochlorite for 10 min during 15 days. Microbiological tests were used to isolate C. albicans and SGM. Mann–Whitney and Wilcoxon tests were used to compare the mucosal characteristics and Fisher test and McNemar test to compare C. albicans and SGM levels. Statistical analysis at the 95% confidence level (P < 0·05) showed that: (i) the association of coconut soap and 0·05% sodium hypochlorite significantly reduced clinical signs of denture stomatitis, (ii) C. albicans did not reduce in counts, (iii) SGM were reduced but not significantly and (iv) the association of coconut soap and 0·5% sodium hypochlorite was effective in controlling denture biofilm

-- end quote --


Second article:

-- quote --


The effect of untreated and enzyme-treated commercial dairy powders on the growth and adhesion of Streptococcus mutans

  • a School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Ireland
  • b School of Biomolecular and Biomedical Science, University College Dublin, Ireland
http://dx.doi.org/10.1016/j.lwt.2011.01.025

Abstract

Dental caries is a common bacterial infection, but the progression of this disease can be delayed by preventing initial attachment of cariogenic bacteria such as Streptococcus mutans to tooth surfaces. This study firstly compares the effect of untreated (UT) and enzyme-treated (ET) dairy powders on the adherence of S. mutans to hydroxylapatite (HA), an analogue of tooth enamel. A fluorescence-based method was used to quantify adherence of S. mutans to HA both in the presence (S-HA) and absence (PBS-HA) of saliva. Secondly, binding of proteins present in the test materials to HA was quantified using bicinchonic acid assays and SDS-PAGE. In addition, the effect of UT and ET dairy powders on growth of S. mutans was examined using an optical-density based assay. UT acid whey protein concentrate (WPC) 80, sweet WPC80, buttermilk powder (BMP) and cream powder (CP) significantly (P < 0.05) inhibited adhesion of S. mutans at ≥31.25 μg mL−1 in the presence and absence of saliva. ET dairy powders were less effective inhibitors of adhesion, but ET sweet WPC80 significantly (P < 0.05) inhibited growth of S. mutans at ≥0.6 mg mL−1. Therefore, due to their adherence- and growth-inhibitory properties, dairy powders may be beneficial in the treatment of dental caries.

-- end quote --


Of course if you're using milk powders make sure to avoid imports from asia with the kidney-stone-causing Chinese melamine additives.  Every now and then, some supplier is still busted for reselling tainted product.

What's the enzyme?  Well the article is pay-walled, so someone with access can perhaps summarize.


## Jonathan Cline
## jcline@ieee.org
## Mobile: +1-805-617-0223
########################


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