Re: [DIYbio] Commercial DNA capsules - any experience? Useful or snake oil?

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I remember watching an entertaining yet bothersome TED talk by a guy
who was discussing attempts to extract Dinosaur DNA from bones, and
the "challenges" they faced. Apparently they tried to dissolve the
bones to release the DNA with hot acid, suggesting they never
consulted with a molecular biologist first to learn about acid
hydrolysis. >_<

But yea, the proof is in the archaeology: DNA survives a long time
under pretty harsh conditions, so if you provide something remotely
cushy, you'll have DNA to spare.

On 02/25/2013 05:09 PM, Josiah Zayner wrote:
> As Dakota said, DNA is really stable. Usually in the > 100,000
> year range on ice with nothing special added. People have tested
> this by calculating a rate of hydrolysis and extrapolating.
>
> On Monday, February 25, 2013 9:29:41 AM UTC-6, phillyj wrote:
>
> On Mon, Feb 25, 2013 at 10:21 AM, Jiri Dluhos
> <jiri.blueb...@gmail.com <javascript:>> wrote:
>>
>> Well, I understand, but if their dessicant really guarantees
>> that
> the stored
>> DNA keeps unchanged for years, it's not that bad...
>>
>> Full-genome sequencing costs still about $5400, not a negligible
> amount :-(
>>
>
> I think they get high profit margin off this. Extraction is cheap
> and it looks like they lyophilize the DNA and stick it in a sealed
> tube in a steel cylinder.
>
> The target customers are those who probably think they can clone
> people in the future. Or maybe use the DNA for sequencing in the
> near future (when prices go way down) to determine any genetic
> diseases.
>
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