While thinking about thene therapy once again, one question arised:
Usually, the Adeno-Associated visus integrates into a specific locus in chromosome 19. But the integration site does not seem to be very sequence specific.
Now, what I wonder: Once you had a AAV-gene therapy, you cannot have a second one? Or will the second therapy using the same vector integrate randomly? Or some other place in chromosome 19?
I know that's not diy bio, but a lot of smart people here :D
-- Usually, the Adeno-Associated visus integrates into a specific locus in chromosome 19. But the integration site does not seem to be very sequence specific.
Now, what I wonder: Once you had a AAV-gene therapy, you cannot have a second one? Or will the second therapy using the same vector integrate randomly? Or some other place in chromosome 19?
I know that's not diy bio, but a lot of smart people here :D
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