Re: Ultrasonic Misters -> Sonication?

Here's a nice blog post on a guy building his own power ultrasonic
driver for a 70W transducer bought for $30-40. He's using it for
ultrasonic drilling into ceramics and glass; way more power than
what's needed for sonication.

http://www.imajeenyus.com/electronics/20110514_power_ultrasonic_driver/index.shtml

He's casting, turning and tuning his own ultrasonic horn from aluminum
though - definitely not for the faint of heart...

On Jan 19, 5:47 am, CoryG <c...@geesaman.com> wrote:
> If you need different frequencies you could put together a sort of a
> phased cavity - set two sonicators opposite each-other and adjust
> their position (perhaps epoxy them to the end of a bearing attached to
> the end of a screw to make it quick and easy to tune) - you can then
> control their phase difference by turning the set screw (the bearing
> would just be to ensure the wires don't get tangled from the sonicator
> spinning around).  The power will increase and decrease along with the
> phase angle alignment, so you might need 2 on each side in order to
> get the same power out of them when their about 90 degrees apart
> [note: physical orientation won't necessarily translate to phase
> alignment - in fact it is very unlikely that it will, as the initial
> phase offset will be determined by when the things achieve self-
> resonance relative to one another, and their distance apart] - you
> should be able to see the difference because in all likeliness at 180
> degrees out of phase [disregarding the initial 180 degree offset by
> pointing them at each-other] they won't have any noticeable power
> transfer along the beam-line, however both sonicators will likely be
> louder/vibrate harder - at 0 degree alignment they will be be about
> equivalent to a single sonicator at 2x the power rating - they will
> likely encounter some drift, so you might want to let them sit
> stationary (make sure the screws don't spin - changing their position
> from one another) and measure any noticeable effects of vibration at
> either end or water sputtered up in between them to see if it does, it
> should be pretty low frequency, so the drift shouldn't be that bad,
> but the best chance the driving circuitry is likely to have of being
> phase-matched is if they were made on a production line (cheap Chinese
> sonicators are probably the best solution next to precisely tuned
> phase-matched ones for this reason).  If you can ensure the driving
> circuitry is phase matched you can control the phase angle just by
> keeping them a fixed distance apart and switching them on at different
> times (speed of sound through target medium and the frequency will
> give you the wavelength - which is equal to 360 degrees phase offset).
>
> On Jan 19, 6:53 am, Cathal Garvey <cathalgar...@gmail.com> wrote:
>
>
>
>
>
>
>
> > To date though, has anyone attempted sonoporation or sonication using
> > those or any other form of consumer ultrasound? Were the results
> > negative or positive or inconclusive?
>
> > Sometimes I think we suffer the same problem as conventional
> > institutional science when it comes to failures; nobody reports
> > failures, so we end up repeating and repeating the same approaches until
> > it either works or becomes informal common knowledge that it doesn't.
>
> > I made a curtailed, half-assed attempt at sonicating some oil and water
> > using a mist-forming sonicator yesterday, and it didn't seem to work
> > very well. So, there's my failure report. However, I didn't get a fair
> > chance to try it out, as I was interrupted. Also, it made a huge mess;
> > as John pointed out I think, these things are designed to sputter water
> > everywhere!
>
> > On 19/01/12 11:19, Patrik wrote:
>
> > > There's also theultrasonicjewelry and eyeglass cleaners. Typical
> > > models seem to be 42kHz, 35W, 1 pint (600ml) capacity.
>
> > > On Jan 18, 1:41 pm, John Griessen <j...@industromatic.com> wrote:
> > >> On 01/18/2012 10:24 AM, Cathal Garvey wrote:
>
> > >>> What frequencies do these things operate at?
>
> > >> 40 KHz to 80KHz
>
> > >> I imagine the wattage is
>
> > >>> going to be pretty low on these?
>
> > >> 3 to 10 Watts often
>
> > >> What frequencies and wattages do you
>
> > >>> *need*  to get stuff done like:
> > >>>   - Electroporation?
> > >>>   - DNA sonication?
> > >>>   - Cell disruption?
>
> > >> I'm sure you can get a small sample to do whatever cavitating sonic waves
> > >> will do, and at the small driver wattages found in those mister gadgets.
> > >> The drivers for misting are a little different shape than for waves, but
> > >> close to the same thing.  They probably make a ring focused beam that is
> > >> aimed at the surface of the water reservoir so the surface is disrupted
> > >> into mist, where the usual setup is to make waves that travel and hit
> > >> tank walls or what is in the tank.
>
> > >>> There's usually a water-level sensor on top to prevent them running
> > >>> while dry, which would break the unit, but you could always put it into
> > >>> a sample until entirely wet (without bubbles on the electret), turn
> > >>> upside-down at the surface, and then plug in?
>
> > >> Sounds reasonable.  OTOH, I got some piezo discs for cheap on ebay with experiments
> > >> in driving them as sonicators in mind.  Think 0.05 USD.
>
> > --www.indiebiotech.com
> > twitter.com/onetruecathal
> > joindiaspora.com/u/cathalgarvey
> > PGP Public Key:http://bit.ly/CathalGKey

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