Actually I do mean single nucleotide differences in 0-1000 total nucleotides
On Feb 29, 2012 4:24 PM, "mad_casual" <ademlookes@gmail.com> wrote:
-- Depends on what you mean by electrical method (label-free?), but yes.
The problem isn't sensing single nucleotide length differences, the
problem is sensing relevant single nucleotide length differences in
hundreds if not thousands of bases.
On Feb 29, 3:02 am, Nathan McCorkle <nmz...@gmail.com> wrote:
> Do you think some electrical method could sense single nucleotide DNA
> length differences in a femtoliter scale channel? (1micron * 1micron *
> 2microns = 2 femtoliters)... 1 micron electrodes are easily made with
> standard microfab today.
>
> I know we've talked about a few methods on here before, capacitance
> comes to mind... or maybe impedance
>
> --
> Nathan McCorkle
> Rochester Institute of Technology
> College of Science, Biotechnology/Bioinformatics
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