Science

See in-line responses below.

On Fri, Jan 31, 2014 at 2:26 PM, Eni Idea <eni.idea4@gmail.com> wrote:
> Okay, but still I don't really get it...;)
> So, you say you can almost do anyhting you want ..you mean at home?

Yes, almost anything, except the exceptions. Because the government
has a strong State level presence, meaning sometimes State laws can
supersede Federal law, laws and their enforcement vary throughout the
country. Then there are counties, towns, villages, cities. All can
have laws, but generally these cannot supersede State or Federal (i.e.
reduce restrictions), only add restrictions.

This article looks pretty good upon first glance, zoning and
home-business are keywords here (just because :
"Is Your Home Zoned for Business?"
http://www.entrepreneur.com/article/68844

"Types of Zoning"
http://realestate.findlaw.com/land-use-laws/types-of-zoning.html


> One of
> the most important things is: is there, e. g., a special agency that really
> has control over your work?

Only if you start breaking laws do agencies get specific, or a certain
locality has a law saying you need to have permission. There are
Federal laws about Animal welfare, but even this depends on the
Zoning, i.e. if you're technically a farm things can be different.
This would be handled by the USDA, who also handles GMO plant stuff:
http://www.aphis.usda.gov/about_aphis/



> And are all guidelines (NIH; CDC; BMBL;) only recommendet or required if you
> don't research at an institution?

They are recommendations, period. Institutions follow them because
they're generally good recommendations, and they'll get sued for
negligence if something were to go wrong and they weren't following
industry-accepted best-practices that might have prevented the
accident.

The same would apply to an individual who was within their rights of
the law to perform experiments, if they screw up and were found to be
lazy with some safety mechanism, they'll likely be sued/jailed. Some
biotech/chemical companies break the law year after year, but simply
pay the fine since their profit is large enough. Sometimes these
companies eventually get taken to court to face shutdown if their
practices don't change, or they jail the CEO or whoever blame falls to
legally.

OSHA would also be a good research topic for you, but I think this
might only apply if you're paying someone to work:
https://en.wikipedia.org/wiki/Occupational_Safety_and_Health_Administration#Health_and_safety_standards

> So let's say you want to establish a community lab, can you open a BSL 1 -
> lab without any registration and expertise or is there an agency for the
> autorisation process?

Maybe, a knowledgeable 'Agent' could be a local lawyer, or as the
entrepreneur.com article says "The first step is to call or visit your
local municipal building and ask to see copies of the ordinances that
apply to home occupations". (or other home/residential ordinances)

> Another question: you mentioned city laws, are there really special laws for
> each bigger city and if so, what are they mostly about?

Yes, they vary by city and by region. The range of topics varies too,
anti-cloning, anti-guns, anti-explosives, anti-GMO, anti-nuclear. If
some group of people can convince the local population and achieve
majority vote, most anything can become a law. Some places pay you to
install rain-water capture barrels, others make it illegal, and it
depends on the property's zoning and extent of development:
http://blog.heritage.org/2012/08/07/when-it-rains-in-oregon-the-state-owns-the-raindrops/
www.naturalnews.com/029286_rainwater_collection_water.html

"Oregon graciously allows Oregonians to collect water from artificial
impervious surfaces (rooftops, parking lots, etc.) and feed it
directly into rain barrels."
"But if that water touches the ground, it is the property of the state
of Oregon, and you cannot collect it without a permit. Since Oregon
owns it, using it without permission would be a form of stealing."




See this *great* overview by Raymond:
http://chimera.labs.oreilly.com/books/1234000001995/ch07.html

"
Even in the US, there is a patchwork of regulations dependent on where
you live, although this is the exception rather than the rule. In
California, at the state level, human reproductive cloning is banned,
with a fine of $1 million levied for violations, making it
prohibitively expensive to raise a large clone army in the Golden
State. (Protip: Nevada does not even prohibit the use of state funds
for human cloning, borders California, and the available huge tracts
of desert land may be more suitable for a secret underground lair.)
Note that most of these laws have monetary fines rather than criminal
penalties. A few federal regulations exist, but most of these also
lack criminal teeth. They use the carrot of federal funding to enforce
experimental standards or restrictions. Bans on funding for
reproductive human cloning and the reversed ban on using particular
cell lines for stem cell research are good examples of using funding
carrots to enforce limits on research.
"

"
What will probably have more impact on you is where you interface with
your local utilities and services infrastructure. Most local
governments (at the city, county, or water district level) have
regulations about what's OK to dump down the sewer or throw in the
trash. What is hazardous, and how do you dispose of it? The short
answer is: if you'd be uncomfortable spilling it on your dining room
table, don't just flush it or throw it away. Check with your local
water and trash authorities about the best way to proceed. For
instance, most water authorities require that residential wastewater
result from basic activities like washing and not contain hazardous
waste. Specific restrictions may include things like allowable range
of pH, anything that can catch on fire, materials that might cause
obstructions, and even the color of the water.
"
"
Finally, in the US, the last resort when people are hurt or property
is damaged is often hiring a lawyer and suing someone. If you burn
down your apartment building, it really doesn't matter if it's from a
lamp you badly rewired or if you left an alcohol lamp
burning--something you could have prevented burnt several homes to the
ground, and you may be liable.
"

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The demo Q and A thing seems like it would be better made with
something that evolved from HyperCard... this online 'story writer'
program seems like it would be perfect for actually getting biologists
to write some great info into one of these things.

http://writer.inklestudios.com/stories/4vp5
http://writer.inklestudios.com/

On Fri, Jan 31, 2014 at 3:16 PM, William Heath <wgheath@gmail.com> wrote:
> Hi All,
>
> I have created an asrynchronous backward chaining rules engine html5 rich
> internet application that interprets prolog rules. I am using to create an
> expert system for diybio. It is fully opensource and I have the beginnings
> of the expert system here:
>
> http://plnkr.co/edit/yuZkr6VoKWswAp7KM3mt?p=preview
>
> If your not familiar with plnkr, you can just fork it and then save it to
> make changes. Check it out and add to it!
>
> -Tim
>
> P.S.
>
> Please share your additions with the community.
>
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--
-Nathan

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On Fri, Jan 31, 2014 at 1:44 PM, Cathal Garvey
<cathalgarvey@cathalgarvey.me> wrote:
> I imagine a modified tobacco with pest or fungal resistance would be big
> money, but then you'd be one of the bad guys for helping make more
> cigarettes in the world. :)

'Better Cigarette' GMO? Throw some caffeine in there, pull in the
coffee market. Mellow Methyl Salicilate 'natural menthol' smokes, or
Intelligent Isoamyl Acetate (aka Bursting Banana) flavor. Some
biosynthetic combustion product that scrubs carcinogens from the
smoke.

This is fun!

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Hello,

Hope you are doing well
Please go through the following requirement and please let me know on recruiter@tcagroupmail.com if you have any available candidates

Role : ETL Developer
Location : Brooklyn, NY

SCOPE OF SERVICES

The scope of services to be performed by the selected individual includes:

·         Work closely under the direction of the Project Manager with stakeholders from Housing Recovery Office, OMB, DoITT, the Mayor’s Office and other stakeholders including managers, line employees, and IT staff.

·         Responsible for designing and maintain ETL code using Informatica

·         Work with the Team Lead to ensure that the right solution is put in place as per design

·         Should be able to understand and follow the technical design documents and update them, if needed, during the development phase.

·         Execute development plans and revise as appropriate to meet changing needs and requirements.

·         Modify existing programs to confirm to system changes or to make improvements in the existing program.

·         Write and maintain documentation to describe program development, logic, coding, testing changes and corrections.

MANDATORY SKILLS / EXPERIENCE:

·         At least 4 years of overall development experience

·         Must have 3+ years of ETL experience and Business Intelligence experience.

·         Must have Informatica PowerCenter development experience

·         Must have Informatica B2B Data Transformation development experience

·         Ability to Design, Develop and Deploy the ETL processes and performance tune ETL        programs/scripts

·         Strong knowledge of XML, XML Schema, XSD, XSLT/XPath and BI and Data Warehousing concepts

·         Strong experience in Oracle, PL/SQL

·         Unix shell scripting

·         Must be able to see tasks through to completion without significant guidance.

·         Must be able to provide documentation on their work.

DESIRABLE SKILLS/EXPERIENCE :

·         A Bachelors or Masters degree in MIS, Computer Science, or equivalent experience is desired;

·         Knowledge of Java/J2EE is a plus

·         Knowledge of Jasper Reports, OBIEE

·         Experience with formal SDLCs and business analysis methodologies;

·         Working knowledge of business analysis documentation standards;

Thanks,
Shalin
TCA CONSULTING GROUP
recruiter@tcagroupmail.com
908-448-0874

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I imagine a modified tobacco with pest or fungal resistance would be big
money, but then you'd be one of the bad guys for helping make more
cigarettes in the world. :)

On 31/01/14 21:35, Nathan McCorkle wrote:
> On Fri, Jan 31, 2014 at 1:21 PM, Koeng <koeng101@gmail.com> wrote:
>> Any particular reason you like tobacco over arabidopis? Sorry, I am not
>> really into plant biotech so I don't know a lot of the differences
>
> Maybe because it's a commercial crop more data exists? More commercial
> value if the inventor comes up with some awesome GMO?
>

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On Fri, Jan 31, 2014 at 1:21 PM, Koeng <koeng101@gmail.com> wrote:
> Any particular reason you like tobacco over arabidopis? Sorry, I am not
> really into plant biotech so I don't know a lot of the differences

Maybe because it's a commercial crop more data exists? More commercial
value if the inventor comes up with some awesome GMO?

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This, if confirmed, it the news of the year!

That sounds feasible (and legal) to do in your basement.
Some time ago we talked that you shouldn't inject yourself your own stem cells. But would they really develop into cancer? their p53 and ras was not mutated so they should just remain stem cells. Or differentiate (more likely)

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How big is too big? I have some tobacco that gets about 1 to 1.5 feet
tall. I'm not sure if it's actually a dwarf variety or if I'm just
stunting the growth by planting in small pots. But even if I am just
stunting it, it's able to flower and produce viable seeds.

-cory

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