[DIYbio] Re: Immersive protein structure analysis with Microsoft's HoloLens

Hi Brian,
The HoloLens actually projects the images into your eyes so you "see" the 3D model in front of you. You can walk around the model as well as reach out and "touch" it.  It is different from VR devices like the Oculus in that you can actually see and walk around the room - an ability that is great for in situ gaming but may not be necessary for protein modelling. The TED talk linked in my first post above gives you an idea of how it works. 
Last Saturday evening we tried to upload STL files (the Zika viral coat protein and the smaller Ubiquitin) exported from VMD to the HoloLens. This required uploading first to Microsoft's OneDrive. Unfortunately, the HoloLens couldn't connect to the MS guy's OneDrive account and he thinks it is because the development version of the HoloLens was configured to only connect from within the MS internal network (or it was a bug). He is back in Redmond so when he has time he will try uploading.
I opened the STL protein structure files in the Slic3r 3D printer app and a lot of the goodness in the Protein DataBase file format was stripped out. Not surprising since STLs were designed for 3D printing and not molecular modelling. I think the STLs are fine for basic introspection of the structure model but if you want to, say, highlight acidic amino acids in the structure then you are stuck. This means there is an opportunity for someone to write a HoloLens app that the reads in the native PDB xml file format and provide gestural tools for handling and manipulating the models.
Cheers,
Scott


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