Yes they have compared whole genomes not only from existing apes but also from ancient humans (neanderthals, etc.) with modern humans.
There has been quite a bit of focus on genes that are different from other apes to figure out what are "human" genes (http://science.sciencemag.org/content/360/6393/eaar6343). Also another interesting discovery is that RNA splice forms are quite different even though the gene is essentially the same (https://www.ncbi.nlm.nih.gov/pubmed/28957512). We are still scratching the surface of genomics! Pretty exciting time!
BTW, percentages are not useful metrics when the numbers are large. For example, about 1-2% of our genome codes for proteins. So a metric such as 1% difference in chimps and humans does not mean much because that 1% difference may all be in coding genes - this is not true of course - but just to give you a sense of how numbers can mislead. Another example of percentages being misleading is anti-bacterial soaps etc that say that 99% of bacteria are eliminated. the amount of original bacteria may be 10e7. So if I have got rid of 99% I still have 1,000,000 bacteria remaining!
On Wed, Aug 29, 2018 at 5:51 PM Henri Lentonen <lentonen.henri@gmail.com> wrote:
Hello,--
have they compared more than 1% of human and chimpanzee DNA already?
Also I dont find anywhere, how many percent is chimp DNA already sequenced.
As here only 1.9 million base pairs was compared, it is about 0.06% of the whole genome. Why only so little can be compared?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC379137/
Also this is noteworthy:"98.6% sequence identity drops to only 86.7% taking into account the multiple insertions/deletions (indels) dispersed throughout the region. "
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