Re: [DIYbio] I'm currently working on changing the world!

Before spending any time fabricating or building, run some napkin math
with real-world fudge factors. I remember this style of heater (maybe
on evolver itself) was discussed before (the sleeve). Do you really
believe that the laws of physics allow precise temperature control of
a piece of aluminum which touches a "heating resistor" and is
close-loop controlled by a thermistor? I do not. Not at all. It
might look pretty in the pictures. Feel free to prove me wrong, thats
what science is all about. Perhaps it's a question of "whatdya mean by
'precise'? Works well enough in the uni lab.." (which itself is a
carefully temperature-controlled environment of 20C)

The motherboard is not complex, it looks like simply a bunch of
connectors and resistors. I guess it is supposed to plug daughtercards
in. It is a large and unnecessary expense. Maybe they had a large
grant award and felt no need to constrain the budget. There's no need
to make that PCB. Any real lab will specialize in a particular area
of experimentation, with a well defined and limited set of protocols,
and thus will not need so many variations of arbitrary plug-in boards.
Just point-to-point solder together what is needed. Cabling is far
easier and in most cases more reliable (consider RF noise, crosstalk,
power distribution) and less expensive compared to building a
backplane interconnect system (which is what the evolver design seems
to represent). Should any design really use a backplane of long
traces for analog lines (ADC or DAC)..probably not.

There have been other prototype systems similar to this built over the
years and discussed in this group.. including much-hyped ones, MIT
etc.. call up the original lab and ask if they still use the machine,
they will say: No, it's sitting in a corner covered in dust. Due to
various aspects of practicality and design failure.

On 3/23/19, Dakota Hamill <dkotes@gmail.com> wrote:
> https://www.fynchbio.com/tutorials/2018/7/1/building-a-smart-sleeve-for-continuous-culture
>
> On Sat, Mar 23, 2019 at 1:35 PM Dakota Hamill <dkotes@gmail.com> wrote:
>
>> That motherboard seems pretty intense being a non EE. Would be cool to
>> recreate just a single reactor with that sleeve and the arduino.
>>
>> On Sat, Mar 23, 2019 at 1:24 PM Jonathan Cline <jcline@ieee.org> wrote:
>>
>>> It would be better to ask /does it actually work/ first, because there
>>> is the small burden of proof and reproducibility regardless of lab
>>> publication. https://www.fynchbio.com/documentation
>>>
>>>
>>> On 3/23/19, S James Parsons Jr <sjamesparsonsjr@gmail.com> wrote:
>>> > Does anyone know if eVOLVER has a website showing how to build one?
>>> >
>>> >

--
## Jonathan Cline
## jcline@ieee.org
## Mobile: +1-805-617-0223
########################

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