[DIYbio] "Lab Grown Dairy Is Here".. synferm ice cream

"A third startup, Motif Ingredients—a spinoff of Gingko Bioworks—is
using $90 million in funding to focus on lab-grown dairy proteins as
flavor and texture ingredients."


This same topic on a consumer site, says:
"They 3-D printed a cow's DNA and inserted it into the yeast."
Umm, how about, nope.



bloomberg.com

Forget Synthetic Meat, Lab Grown Dairy Is Here
Consumers spend billions of dollars on protein derived from dairy.
What if they could get it without using cows?
By Larissa Zimberoff
July 11, 2019, 6:00 AM PDT


The search for sustainable, healthy alternatives to meat currently has
two paths: the meat-mimicking veggie burger and lab-grown proteins.
But in the land of dairy, there's only plant-based alternatives like
cashew "butter" and almond milk.

Whether you're milking them or slaughtering them, industrial cattle
husbandry is bad for the planet. Studies show it to be a key culprit
in the climate crisis and a source of localized environmental damage.
The refrigerator aisle has been full of plant-based dairy for some
time, but now there are a few startups who, like the purveyors of
cultured meat, want to take dairy one step further.

Already under siege by falling milk sales, Big Dairy lobbyists have
been lashing out at makers of plant-based rivals as they grow
market-share. But their next enemy may be coming from the laboratory,
in the form of synthetic whey, and investors are already lining up.

While fewer people are drinking cow's milk, they're still eating
yogurt and cheese, and a crucial protein that comes from making those
products is whey. It's relatively flavorless and incorporates well
into a range of food formulations for everyone from infants to adults.
There's already a huge market for it, as demand for whey protein and
whey-based products is on the rise thanks to consumer demand for
protein in everything, from bars to shakes.

The U.S. is the single largest exporter of whey products, with
estimated sales of $10 billion last year. BCC Research said the
category will grow by 6% annually through 2023. But for all its
popularity, all that whey still comes from cows, a fact increasingly
seen as a liability for climate- and health-conscious dairy and
protein lovers.

Ryan Pandya saw an opportunity in this consumer conundrum. He wants to
be the first to market a non-animal whey protein through his San
Francisco area-based company, Perfect Day. Like other food startup
founders, Pandya and partner Perumal Gandhi are both vegan. Rather
than forego the taste of real cheese and dairy for poor vegan
substitutes, the pair decided to invent their own version of the real
thing. The startup focused on the well-worn food path of microbial
fermentation—harnessing custom yeast and bacteria to grow the proteins
that make milk taste like milk.

But first, the company and others like it face some big hurdles:
consumer squeamishness and regulatory reviews that may end up focusing
more on the genetically modified organisms [GMO] used to make
lab-grown whey.


Five years ago, Perfect Day joined the synthetic biology accelerator
IndieBio as it searched for microbes that could be engineered to make
functional milk proteins. Today, it has more than 60 employees, $60
million in funding and says that it's produced one metric ton of
lab-grown whey (for scale, the U.S. uses more than 200,000 metric tons
of all types of whey annually).

Late last year, agriculture giant Archer Daniels Midland agreed to
invest in Perfect Day as the startup seeks to lower the cost of making
whey. "When you're creating something that already exists, there is
already an established price point," said Victoria de la Huerga, vice
president of ADM Ventures. "The goal for companies that are leveraging
new technology to make new food is you have to make it affordable."

Though it's still early days, Perfect Day contends its proteins
require 98% less water and 65% less energy than that required to
produce whey from cows. The company said it hopes to one day license
its ingredients so they can be used by food manufacturers in a range
of products—but those involved concede that scaling the effort won't
be easy.

Still, Perfect Day Chief Technical Officer Tim Geistlinger said the
process is "fully adaptive—you can do it anywhere in the world and it
doesn't matter how hot it is." Having come over from plant-based
burger maker Beyond Meat, Geistlinger argued that "if you want to
raise your flag on sustainability or tolerance to climate change, this
one solves a lot of things."

While Perfect Day wants to be an ingredient supplier, food startup New
Culture wants to make the end product: cheese from its own lab-grown
casein, another protein derived from dairy. In the lab, New Culture
has crafted a super stretchy, believable version of mozzarella—the
most consumed cheese in the U.S. A third startup, Motif Ingredients—a
spinoff of Gingko Bioworks—is using $90 million in funding to focus on
lab-grown dairy proteins as flavor and texture ingredients.


Matt Gibson, the New Zealand born founder of New Culture and a
self-described committed vegan, said he didn't like the non-dairy
options on the market. "I just don't think you can make cheese with
any of the plant-based proteins," he said.

There's even a nonprofit working on lab-grown whey. Real Vegan Cheese,
based in Oakland, California, has been researching how to make
multiple casein proteins with bacteria, and plans to do the same with
yeast. The group said it wants to disseminate its recipe so others can
develop their own sustainable, animal-free dairy products.

Non-animal whey protein is new, and may require scrutiny by the U.S.
Food and Drug Administration. But Nigel Barrella, a food industry
lawyer who is of counsel to the Good Food Institute, said lab-made
whey will be viewed by regulators as simply another GMO food product.
Last month, Perfect Day filed a General Recognized as Safe petition
(GRAS) with the FDA, a voluntary request for government review.

"In terms of the FDA's attitude, it will be near the GMO product:
functionally these are the same," Barrella said, using corn as an
example: "There is no scientifically known difference between corn and
GMO corn."


But there's still branding to worry about. Few people like to eat
something with "lab-grown" on the label, and vegans will likely steer
clear of something labeled "milk protein." As a result, Perfect Day
wants to rebrand microbes used in food—yeast, fungi, bacteria—as
flora, a more consumer-friendly term.

"We are trying to explore how we can get a term for this industry
that's outside of plant-based," said Pandya. "Something someone with a
plant-based diet can eat, but it's not from plants. It's an animal
protein, but not from animals."

The company plans to start building its public profile by selling
1,000 pints of ice cream made with lab-grown whey, via its website.
"Most of the functionality in ice cream or cream cheese is all about
the whey proteins and how it operates with air and water," said
Gandhi.

Still, Nate Donnay, a Minnesota-based director of dairy insight for
INTL FCStone, doesn't see non-animal whey grabbing huge market share
soon. "Sitting here in the heartland, no one is caring where the
protein came from. They want it cheap and they want a lot of it," he
said. Donnay added, however, that "if you can get cost down and the
functionality there, the big companies will take it."

Barrella, the food industry lawyer, said lab-made whey makers should
play to their strong suit.

"I think it will be sold as a benefit of the product—lower
environmental footprint," Barrella said. "It will be incumbent on the
producers of these products to market the benefits of these products:
milk proteins that don't come from an animal."



end quote



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