That's assuming a lot and injecting unnecessary hostility into an academic query. If barbituate-type drugs or GABA -affecting drugs actually did have an effect, it wouldn't really matter whether the drugs themselves were still available: the question would be "why", and the answer to that might lead to useful solutions that had nothing to do with barbituates or GABA.
My guess would be that it's a spurious correlation and that given the difficulty of simulating binding efficiencies, it's not worth pursuing at the molecular/computational level until more research is done into the real-world observations. But discarding a query by speculating about malicious intent where there's really no evidence of same..isn't helpful.
April 1, 2020 8:34 PM, "Sean Rowshandel" <rowshandelsk@mymail.vcu.edu> wrote:
My guess would be that it's a spurious correlation and that given the difficulty of simulating binding efficiencies, it's not worth pursuing at the molecular/computational level until more research is done into the real-world observations. But discarding a query by speculating about malicious intent where there's really no evidence of same..isn't helpful.
April 1, 2020 8:34 PM, "Sean Rowshandel" <rowshandelsk@mymail.vcu.edu> wrote:
He's using him. You don't understand what this acquaintance asked him to do, clearly, and are putting salt on the wound. That drug isn't even on the market anymore. Even if it blocked the spread of covid-19 if you take enough to COMPLETELY saturate ace-2 and it didn't kill you, if it even binds to ace-2 at all (which I haven't taken the time to look up), it's not on the table. The person either is smart enough to know he's making fun of him, or just a regular old liability to society.
On Apr 1, 2020, at 3:04 PM, Cathal Garvey <cathalgarvey@cathalgarvey.me> wrote:--
"Your friend" sounds a bit accusatory, why the hostility?
On 1 April 2020 19:13:25 GMT+01:00, Sean Rowshandel <rowshandelsk@mymail.vcu.edu> wrote:This is a dangerous drug so no wonder you used the word dilletantic because it describes your friend
On Apr 1, 2020, at 12:35 PM, "Andreas "Mega" Stuermer" < andreas.t.stuermer@gmail.com> wrote:Hi everyone -A friend asked me for a simulation to see if the drug methaqualone will bind to the SARS-entry receptor ACE2.Does anyone have a lot of experience in molecular modelling to predict binding?I feel the way I would do this would be dilletantic.Would love to hear your feedback
--
Sent from my Android device with K-9 Mail. Please excuse my brevity. --
-- You received this message because you are subscribed to the Google Groups DIYbio group. To post to this group, send email to diybio@googlegroups.com. To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com. For more options, visit this group at https://groups.google.com/d/forum/diybio?hl=en
Learn more at www.diybio.org
---
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To unsubscribe from this group and stop receiving emails from it, send an email to diybio+unsubscribe@googlegroups.com.
To view this discussion on the web visit https://groups.google.com/d/msgid/diybio/A1A83D79-7540-4EDD-B104-1C17A6B52A62%40cathalgarvey.me.
-- You received this message because you are subscribed to the Google Groups DIYbio group. To post to this group, send email to diybio@googlegroups.com. To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com. For more options, visit this group at https://groups.google.com/d/forum/diybio?hl=en
Learn more at www.diybio.org
---
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To unsubscribe from this group and stop receiving emails from it, send an email to diybio+unsubscribe@googlegroups.com.
To view this discussion on the web visit https://groups.google.com/d/msgid/diybio/f4069796-0f14-4e38-89ee-8e0cf73e82d6%40mymail.vcu.edu.
0 comments:
Post a Comment