Re: [DIYbio] Electronic and other old fashioned lab notebooks in and out of formal settings

Hi Daniel,


I think this is a critical issue, thank you for raising it. 

I personally use Onenote as my electronic laboratory notebook (ELN), which is fairly unstructured. It would be nice to have something with more structure (i.e. templates), and a very flexible API for plugging in workflows and other pieces of software.

I think there are very interesting developments in the "notebook" space, i.e. Notion (https://www.notion.so ; https://en.wikipedia.org/wiki/Notion_(productivity_software)) , Roam (https://roamresearch.com ), Obsidian (https://obsidian.md ), Craft (https://www.craft.do).

Presumably, life scientists & DIY biologists don't need to reinvent the wheel to take electronic notes. 

I think, for a long time there were concerns about having "signability" and "traceability" for patents, so commercial ELNs used in Pharma had to include those. But, from my understanding now, at least in the USA & much of the world, patents are "first to file", rather than "first to invent", so I'm not sure how relevant these patent-induced notebook requirements are anymore. 

Over the the Laboratory Open Protocol (LabOP) language project, https://bioprotocols.github.io/labop/ , we have been trying to come up with a way to describe biological protocols in software.

A absolutely beautiful thing, would be if executing the protocol, also automatically put the results into your "electronic lab notebook", but we (LabOP) are a very long ways off from that I think. Anyway, I mention it as I'd be happy to continue the discussion, both in the context of LabOP, and outside of it...

All the best,
-Tim
___________________________________
Timothy R. Fallon, PhD
NIH NRSA Postdoctoral Fellow - Moore Laboratory

Center for Marine Biotechnology and Biomedicine 
Scripps Institution of Oceanography 
University of California, San Diego 

tfallon@ucsd.edu
Google Scholar publications and citations
Website: http://photocyte.github.io
Pronouns: (he/him/his)

** I may send emails at odd hours due to my own flexible schedule. I respect your working patterns and do not expect responses outside of your working hours. **

On Oct 24, 2022, at 7:44 AM, Dan Kolis <dankolis@gmail.com> wrote:

Here's an open procedural; question....

Whether its a formal institution trying to rally work of hundreds or people or a BIYer, notes in life sciences matter.

So, Im working on software and a side component of it is to populate electronic notebooks. The only one I can visualize in Jupyter really. the commercial ones I have looked at seem pretty yawn ready and expensive re ongoing costs...

Also a modality is real time completely, so some work has audio and probably video 'open wire; and shared ( started anyway ). I see both as adjunct functionality to the baseline work.

Anybody run into taking notes, the technology ofit, seriously ? Like a blog maybe, master document for planning etc.

Planned in is also forensic identity verification, so any sequence or PDB etc can't be mistakenly altered. That is, any change can be detected witout people overhead as it occurs.

I think serious researchers would generally like each others notebooks rather then formal papers most of the time. the magic is in the greasy uncertainty.

DIY here as a theme is understood, however, the base of life scienc people can be pretty docrinaire, this is an open ... :Huh first question.

ex question, are pair notebooks, one notes, versus Jupyter, etc .... worth it ? What about old timer sorta, who like paper ? Is a endless fat paper book in chrono order just scanned better then a Jupyter ? Is fussing with little programs a waste of time compared to paragraphs of vague maybe this maybe that, reasoning ?

Audio inserts.

Regards to all,
Daniel B. Kolis




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