Re: [DIYbio] New subscriber to mailing list

Greetings!


Thanks for your response and asking for details, Daniel.

There's nothing secret about my project. This has been done previously by research groups in academia but there are no off-the-shelf tools available for such analyses than can be downloaded, installed, and executed.

Here's a simplified outline of what it is I am trying to achieve, indicating what skillsets I wish to leverage from my collaborator(s):

1. DNA sequences can be 'encoded' in various ways - e.g. one-hot encoding, integer encoding, etc.
2. These encodings can then be transformed into digital signals using techniques such as Fast Fourier Transform, discrete wavelet transform etc.
3. Such digitized signals can be aligned for comparison in ways similar to pairwise or multiple sequence alignment of nucleic acid or protein sequences
4. Furthermore, such encoded and transformed DNA sequences may be aligned , or clustered, or used to identify genomic 'features' of interest, and even 'classify unknown' sequences, and other such bioinformatic applications.

If you have any or all of the skillsets, especially if you come from the electronics digital signal processing field, then please connect with me at this email address. Thanks in advance.

Cheers,
Anand K.S. Rao, Ph.D.


On Saturday, March 11, 2023 at 11:11:05 AM UTC-5 dank...@gmail.com wrote:

Welcome. Yet I remark you have to name what your trying to to to solicit help.

Secret projects generally do not promote collaborators !

There isn't a lot of traffic on the blog, but its basically always quite informed stuffola.... both the stimulus and response(s) really

Regards,
Daniel B. Kolis

 

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