Re: [DIYbio] Can a plasmid contain antibiotic synthesis and resistance genes?

On Tue, Jan 29, 2013 at 1:37 PM, Sebastian Cocioba <scocioba@gmail.com> wrote:
> IIRC the antibiotic is first taken up and then gets degraded so the
> resistance is internal.

Right, resistance is internal, provided by the gene on the plasmid.
The antibiotic wouldn't have to be 'taken up' in this case, only
pumped out.

Obviously the organisms we've discovered antibiotics in, are resistant
to those they produce.

> Seems like its analogous to plugging a battery into
> itself. It would only waste energy? I may be wrong though. Let me find some
> refs.

If you call transformant selection a 'waste' of energy, otherwise
you're 'wasting' money on expensive reagent companies.


--
-Nathan

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