Re: [DIYbio] De extincting dinosaurs or at least extict birds

Certainly not today, maybe in 20-30-40 years, but I would not bet on this.
You can read the genome today, but how would you re-create it?
Re-assembling DNA extracted from bones/eggs is just out of question.
One way would be to find a close relative of the moa, and replace some
of its genes one by one. Does not sound too easy. Do we have a
reliable method of replacing large pieces of eukaryotic genome in vivo
already? How do you identify which parts are important and which are
not? The difference is almost certainly a lot more about regulation
than about changes in proteins. Even if we could do this, it would
still take ages to perform the modify-check cycles, and one could
always claim that the result is not really a moa, but a GM ostrich
made to look like one.
An other way - synthesize the whole genome. I'm pretty sure we can't
synthesize anything remotely as big as a chromosome, and even if we
could, there's a lot more than just DNA in a chromosome, and a lot
more then just the sequence that's carrying the information. If
developed, this technology would be really interesting, and also
really controversial (you could synthesize a human genome), but I
doubt that we will see it any time soon.

On Sat, Jul 13, 2013 at 12:10 AM, Mega <masterstorm123@gmail.com> wrote:
> Just saw a film on TV that T-Rex bones were found which still contained few
> proteins like collagen. Then I read that this is very controversial, if that
> is not contamination.
>
> Then I came across this...
> http://canterburyheritage.blogspot.co.at/2009/01/extinct-moa-to-be-brought-back-to-life.html
>
> The giant bird, Moa, is relatively new extict and there should be plenty of
> sources for DNA... Even eggs are said to be still there.
>
>
> I assume there won't be any cells any more that are still alive...? Is it
> possible to purify the chromosomes, insert in a living cell? I assume that
> it would be near-to- impossible in a diy-setting, because the DNA will be
> damaged at least to some degree...
>
>
> However, from the legal point of view, this should be perfectly legal (while
> inserting GFP into E.Coli is a capital crime)...
>
>
>
> Any opinions on this?
>
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