[DIYbio] DIY Biological Computing

So, has anyone on here thought about doing some of their own biological computing? 

I wonder how hard it is to make a simple 'adder element' with a plant, or bacteria, or something similar. So that when you stimulate it with two certain patterns (representing numbers) in a certain specific order or place(s) it results in the correct pattern representing the addition of those two numbers. 

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