[DIYbio] Choosing Projects By Awesomeness (Was: Real Vegan Cheese)

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Indeed; I'm not working on IndieBB, as I failed to raise sufficient
funding. I'm back to day-job at the moment, although I am trying to
raise support for a biomakerspace in Cork: @formabiolabs on Twitter, if
anyone's interested. If we can raise funds for that, then it'll keep me
busy hacking and attracting impressionable people into science for a
while longer.

As far as the "awesomeness" of IndieBB, I never meant to do it because
it would be awesome, but because nobody's yet created a versatile,
built-for-purpose cloning platform for DIY-Synbio. In other words, I
feel something like IndieBB needs to exist to help people get past the
annoying legacy issues with most available plasmids that call for
antibiotics or outmoded cloning strategies.

Though, you're probably right; I should have directed my attention
elsewhere, because I'd vastly overestimated the appetite for dedicated
platforms in the DIYbio community at this time. I did write something up
on this basis, and for those pondering which projects to attempt and
which things are likely to succeed, perhaps those thoughts will prove
useful:

http://www.indiebiotech.com/?p=245

On 03/07/14 23:21, Yuriy Fazylov wrote:
> oh i got it. you supervise the team involved with it at Axlr8r.
>
> On Thursday, July 3, 2014 9:39:28 AM UTC-4, Cathal Garvey wrote:
>>
>> On-topic; Hey Patrik, really exciting to see this up! I'll try and rub
>> some euros together to throw your way. :)
>>
>> First up, disclosure; as you probably know, I'm a mentor and design
>> consultant to Synbio Axlr8r teams, including Muufri. I offered them some
>> assistance on their first designs, and may continue offering help.
>> However, I'm not being paid (yet, at any rate), so it's not very
>> intensive assistance and I have no monetary bias, just social!
>>
>> I've been badgering all the teams here in Cork to stay open and to
>> resist the lure of old-guard patent-heavy business, the kind of nonsense
>> that's clouded and delayed biotechnology for decades already. Time will
>> tell how my efforts pan out, but the Muufri guys are here more for a
>> mission (panveganism) than for personal gain, and they tell me they
>> aren't planning to patent their outputs. So, that's pretty awesome.
>>
>> OTOH, you guys are planning to patent, which confuses me:
>> https://wiki.realvegancheese.org/index.php/Real_Vegan_Cheese
>>
>> "We plan to patent and abandon to keep this technology free for everyone"
>>
>> ..it's cool that you want to abandon it, but isn't that what prior art
>> is for, instead? And, by registering a patent in the first place, you're
>> creating a disincentive to those who don't *know* that you've abandoned
>> the patent.
>>
>> Worse, if the patent is held by a legal entity or person who later goes
>> bankrupt or into liquidation, the patents may be forcibly sold to
>> someone who'll quite happily use them to destroy others' livelihoods and
>> innovations.
>>
>> There *is* scope for using patents in an open-source way, by using
>> licenses like the DPL that establish an irrevocable license for use and
>> re-use, but it would be my view that the stultifying impact of even
>> registering patents, and the absence of a "patent metadata" search
>> function for people to know that it's DPL licensed, still makes it a net
>> lose versus simply registering public prior art.
>>
>> Speaking of which, the Muufri guys have been pretty public about their
>> intention to make yeast-produced synbio milk, so it's not even clear
>> that the non-obvious parts of the project are patentable, anymore. Much
>> better to continue spamming all the good ideas onto highly trafficked
>> mailing lists to stymie AppleSoftOogle-style "Embrace Extend
>> Extinguish", and carry on innovating.
>>
>> Anyway, that's my 2c. I'll carry on being everyone's underfunded Jimminy
>> Cricket as unobtrusively as I can, having shared that.
>>
>> On 01/07/14 20:33, Patrik D'haeseleer wrote:
>>> Hi all!
>>>
>>> Come check out the IndieGogo campaign we just started to to fund the
>>> Counter Culture Labs / BioCurious DIYbio team for iGEM:
>>>
>>> https://www.indiegogo.com/projects/real-vegan-cheese
>>>
>>> The goal of the project is to engineer the four major cheese proteins
>>> (caseins) into yeast, express and purify them, combine with water and
>> fats
>>> to form micelles, and then make cheese! No more odd nut cheese
>> substitutes!
>>> *Real* cheese, made from real cheese proteins, made in real baker's
>> yeast!
>>>
>>> We've got a $75 "Biohacker Special" just for this crowd: all the
>> plasmids
>>> and detailed instructions for how to make your own cheese-producing
>> yeast
>>> strain.
>>>
>>> For all you hardcore DIYbio fans, check out the tons of information
>> we've
>>> already collected on our wiki:
>>>
>>> https://wiki.realvegancheese.org/index.php/Molecular_biology
>>>
>>> Please help us spread the word! If you can't afford to contribute, go
>> for
>>> the $1 perk to get our updates and talk about us on your social
>> intertubes.
>>> There's tons of other cool rewards as well: from the obligatory T-shirt,
>> to
>>> some unique 3D printed jewelry (oops - still need to add that one!), to
>>> brainstorming sessions with your favorite mad scientists.
>>>
>>> Or if you know someone willing to spend $10 million to shut us down -
>> well,
>>> there's an option for that too! :-)
>>>
>>> Patrik
>>>
>>
>> --
>> T: @onetruecathal, @IndieBBDNA
>> P: +353876363185
>> W: http://indiebiotech.com
>>
>

--
T: @onetruecathal, @IndieBBDNA
P: +353876363185
W: http://indiebiotech.com