The tatoo delivery method is a very nice low tech idea.
Maybe add PEG or lipofusamin and there you go.
But once you delivered the DNA, does that really means it stays? You stably transformed the skin cells, but they die off and get replaced by stem cells (which may not carry the DNA).
Where do this stem cells "rest" while not needed? Are they between the cells? Can you reach them with tatoo delivery method?
On Monday, June 16, 2014 5:38:28 PM UTC+2, Mega [Andreas Stuermer] wrote:
-- Maybe add PEG or lipofusamin and there you go.
But once you delivered the DNA, does that really means it stays? You stably transformed the skin cells, but they die off and get replaced by stem cells (which may not carry the DNA).
Where do this stem cells "rest" while not needed? Are they between the cells? Can you reach them with tatoo delivery method?
On Monday, June 16, 2014 5:38:28 PM UTC+2, Mega [Andreas Stuermer] wrote:
and that by accident, actually searching for another topic. And by "great" I mean "oh crap". Because I have no idea how to get to try it and how to get it approved :P
It wouldn't integrate into mamalian genome, still be stably mantained a lifetime. But probably, you'll need a gene gun to put it into your skin cells. Or lipofusamin? No allergenic potential at all.
The fun thing is It's below 500 bp.
I guess still another project for archieving :P
If I ever caught that virus I'm so confident this is the perfect therapy, I would probably play guinea pig myself xD
Or is there a way to work on this somehow?
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