[DIYbio] Re: least risky human hello world?


Adding some infrared sensing protein to a virus and putting that into your eye: if you're tying to put the DNA that encodes that protein into the DNA of your eye cells, wouldn't you also need all the associated control mechanisms? Promoters, repressors, etc. You'd have to make sure it doesn't get over expressed or (maybe) you'd just see IR and nothing else. I'm a noob at biotech and not an expert by any stretch of the imagination, but maybe you should try this on fruit flies first. If you need fruit flies, I got some WT's in the kitchen.

Tom.





On Monday, September 1, 2014 6:56:50 AM UTC-7, Mega [Andreas Stuermer] wrote:
Another thing... http://petapixel.com/2014/08/25/retinal-neuroscientists-rebuttal-humans-cant-see-infrared-matter-eat/ This reminded me... 

Take Adeno-Associated virus, put in some infrared-sensing protein. Put it into your eyes and you should be able to see infrared? I saw some gene therapy approaches by AAV. They cannot replicate because they need cells that carry AV proteins. 



It would be also possible to engineer some kind of small Cestoda into something like a Goa'uld, I guess. It may seem be pretty disgusting to me, It would eat a part of your food so you don't get obese. And it could provide you with vitamin K, vitamin C, growth factors.. 
AFAIK if you cut a nerve it won't rejoin because of inhibition. I you add a growth factor (I remember a press article claiming the discovery of this nerve growth factor several years ago), it can rejoin. 
However, not sure whether such a "symbiote" would sense nerve injury in your hand if it lives in the gut...  





On Thursday, August 21, 2014 9:58:33 AM UTC+2, Nathan McCorkle wrote:
Are certain organs less likely to metastasize? Could you rub a virus
onto your hair that temporarily disables your innate dye/dark
compounds to lighten your hair? Or vice-versa, that temporarily
produces dyes in blonde/light hair?

What about something that temporarily changes urine color?
Bioluminescent urine could be pretty neat, it might make evaluating
toilet cleanliness/effectiveness easier (imagine that on kickstarter,
etc...).


--
-Nathan

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