Re: [DIYbio] Re: update on the liquid handler

John, for Otto's design you are offering a projection out of the relatively 2D frame to navigate about a series of cascading shelves. Is that correct?

Guillotine design could probably use the same belt with the added Z axis projection. It would need a suspension bridge support or a brace.

>I don't now if it will be light and slim (to easily pass through the levels), we want a pipette car really light and tight.

Make a smaller but broader pipetter w/ autoclavable parts. What are you losing if the pipette goes in at an angle and then swivels upright into action? Or dare I propose adding some distance between shelves? ;)

Level buildings: I doubt DIYbio community is going to have trouble with a level and a right angle or a string with a load on it. But in case they are, a circular multi tier (typical wedding cake type) workstation on a turnable platform (equidistantly spaced ball bearings needed here for support) could be used. This would make the handler X and Y axis dependent whereas Z for the major part would be left to the cake. Holding containers would have to be custom made. Shouldn't be issue with additive manufacturing.

>It could go blind most of the time, but home in on some targets to calibrate position on each shelf.

Sure, let the apparatus dry run on high speed with [food coloring] or color turning [pH] sensetive liquids. You'd probably even work out kinks in the system that way.

As far as accuracy goes, laser guided (Kinect maybe on a stationary platform) realignment could be implemented for auto alignment, once level.

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I just looked at the YouTube video again. In case I didn't mention it before, that's an impressive piece of machinery, Tom. How will you go about actual pipetter handling? Will it be modeled after commercially available machines?

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