Re: [DIYbio] diy magnetic plate for DNA purification?

On 12/23/2014 10:00 AM, Jeswin wrote:
> unless the magnets the companies use for their stands
> are special for magnetic beads? Anyone know?

Don't know, but how special could it be. The sales blurb
for 96R & 96S Magnet Plates says get the super "S" when you want more speed is all.

Your DIY idea of shoving ring magnets over pipette tip rack tubes sounds
like maybe something to write up. Do they have the same spacing as well plates?
They would if they are for the multi well pipettes...of course...answered my question.

Another way to use magnets would be small slab magnets with the field aiming
out of the flat sides. Those could be molded into a holder so they fit up between wells in
plates. The beads would be in clumps, rather than a ring, but the bottom of the well
would be clear for similar result for pipetting away supernatant solutions.

See this sketch: http://www.ecosensory.com/diybio/magnetic-plate-design-1.png

Speed? From magnets alone? That would come from the magnetic field reaching up into
the suspension from the bottom. Very small magnetic particles coiuld take a long time to move.
So, to speed that up, instead of stronger magnets, one could agitate the whole thing
while magnets are in plalce near the well bottoms. Speedo-presto even with weaker magnets.

With heavy metal magnetic beads in a suspension swirl agitation to stir things is just a natural.

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