Related question, my fiance is naturally brunette and maintains bright unnaturally colored hair. The bleaching process is very high maintenance and damaging, and still results in brassy pheomelanin tones.
I would like to solicit ideas and methods of careful scalp application of rna interference targeting tyrosine 3-monooxegenase. This affects skin as well, unfortunately, so ideal methods spare discoloration of skin beyond the hairline. I'm also interested in ideas for more specific RNAi targets.
On Tue, Mar 10, 2015 at 12:56 PM, Mike Petersen <mike2b17@googlemail.com> wrote:
Hi Alexander,--
I think you refer to the so called "melanocytes" which produce the pigments that give our hair the color.
Found an interesting abstract here:
http://www.ncbi.nlm.nih.gov/pubmed/11602203
Am Dienstag, 10. März 2015 18:44:26 UTC+1 schrieb alexander hollins:I believe it generally ties into the death of the cells responsible for pigment development, and has a pattern similar to death of follicles in male pattern. There are some prevention methods to keep those cells alive longer, but I only know one method thats ever regenerated the dead cels, and it wasn't supposed to.On Tue, Mar 10, 2015 at 9:40 AM, Mike Petersen <mike...@googlemail.com> wrote:Hi DIYbio community,--
I was wondering if there could be any "system-biological" approach to "cure gray hair" and prevent the hair from losing its colour.
What is known about the genetic and the epigenetic mechanisms that cause the colour loss of our hair?
There are some interesting patterns, for example the fact that usually the hair around the temples starts to lose its colors first.
Which expression patterns can be linked to these observations?
And what would be promising ideas to interact with these mechanisms?
Thank you for your ideas
Mike
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