Re: [DIYbio] Re: Help needed: BBC Documentary in need of guidance

Hi Pieter,

Thanks for these, although we could do this I fear it might detract from the focus of the documentary - which is all about the practical applications of synthetic biology and the ease with which people can now begin bio-engineering.

On Thursday, April 30, 2015 at 8:55:01 PM UTC+1, Pieter Waag wrote:
Perhaps you could approach it the other way around, use sound to manipulate growth.

At last year's graduation show of the Royal Art Academy in The Hague Sebastian Frisch presented his Biophonic installation, containing roots of corn that grew towards a speaker.

Or take Matthijs Munnik's microscopic opera based on transgenic C. elegans made in collaboration with the Netherlands Consortium for Systems Biology: https://www.youtube.com/watch?v=TgumhLhfI6g

Also one of the participants in our biohack academy, Giacomo experimented with sound patterns.

On Thursday, April 30, 2015 at 8:07:27 PM UTC+2, Nathan McCorkle wrote:
On Wed, Apr 29, 2015 at 11:34 PM, Jonathan Cline <jnc...@gmail.com> wrote:
> So regarding the radio listening audience.  Any audio will only come from
> the equipment you use.

Well you could poke a stick at a goat, or a puppy... they are biology
that would make audible gas and other noises. There was that blue/GFP
rabbit... though I don't think rabbits make much noise, and while the
bulk of the work could be done in 2 weeks... you'd need a while for it
to gestate.

Chicken embryos are pretty cool, you could easily isolate the heart
and get chunks/cells growing in culture within a day or two... but
you'd need quite the microphone to hear the beating (maybe a piezo
microphone would work if taped directly to the culture dish?)... or
some software to convert a video of the beating heart cells into audio
(I bet this actually wouldn't be too hard with some openCV in Python
or something). But I guess simply dissecting something isn't really
bioengineering.

Chicken embryo heart cells beating in culture
https://www.youtube.com/watch?v=M30-oInTKs4

Beating chick (chicken) embryo heart explant
https://www.youtube.com/watch?v=sJduWqtq-Ts


You could grow some yeast, trap the gas, then emit the gas through a
horn or harmonica... but again, simply growing something isn't really
bioengineering (at least in the media-popular mind).

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