[DIYbio] Re: E. coli chromossome integration

A single pOSIP plasmid (https://www.addgene.org/45985/) will most likely save you 65$ worth of time, and plus you won't have to worry about size. What exactly do you want to integrate?

If you still want to insert your gene using lambda red, put it in/on a defective prophage. Qin/Kim, e14, rac, CP4-57, CP4-6, DLP12 prophages would probably all work. (just looked quickly at E coli genome for these)

-Koeng

On Thursday, October 29, 2015 at 4:00:15 AM UTC-7, Linden wrote:
Hey Guys!

I would like to know how do I pick where in the E. coli chromossome I should integrate my DNA so it doesn´t have any impact on other genes. 

Thank you for you time!

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