The optic systems are going to bounce lasers into your flowcell (glass slide) using a prism so even though you have a good detector, the light itself will be hindered unless you're using Illumina fluorescent labels.
Dakota is right, it isn't the sequencer it's the reagents. Between that and the amount of clogged feed lines you would get on the HiSeq system, it most likely isn't worth the money or the space it takes up.
Probably why people are getting rid of them.
-SG
On Mon, May 7, 2018 at 12:00 PM John Griessen <john@industromatic.com> wrote:
On 05/07/2018 01:27 PM, Brian Degger wrote:
> Apparently it also doubles as a cheap fluorescent microscope :)
> If you want optic systems, it contains a lot of high quality parts.
That "dissection" photo looks like a treasure trove of basic automation systems.
(Lausanne Bio-Hackerspace Hackuarium got a HiSeq2000 (SN# 700918) and Gustavo dissected it.)
https://www.hackteria.org/wiki/HiSeq2000_-_Next_Level_Hacking
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