Re: [DIYbio] Drug addiction biohacking

Ok, I'm liking some of these suggestions. I have another question (anyone can jump in)... can CRISPR CAS9 DIY kits enhance the function of the liver (and other areas of the body) so that the cytochrome P450 enzymes, the ones that destroy and metabolize drugs in the body, can be super enhanced where the quantity of the enzymes are being produced in mega-high quantities? To the point where drugs are being eaten up in a matter of minutes if not seconds if they're introduced in the body?

On Saturday, September 21, 2019 at 1:17:13 PM UTC-4, Nathan McCorkle wrote:

Why not try working to biosynthesize an opioid blocker, like naloxone
or similar, which is synthesized by gut bacteria? Then this
"probiotic" could last quite a while in the gut, until the person
takes too much antibiotic materials. Alternatively you could try using
gene insertion to push this synthesis pathway into whatever cells you
can manage to get it into. Of course getting the biosynthesized dosage
to be correct would require feedback to a gene promoter, etc... which
seems like a pretty tricky part (requiring a lot of testing and
debugging).

On Thu, Sep 19, 2019 at 2:40 PM jackson parks
<jacksonpar...@gmail.com> wrote:
>
> Hello,
>
> Thank you for letting me in. I'm Jack. A friend of mine named Jonathyn recently quit the idea of engaging in CRISPR CAS9 technology because he found out that it can't do anything for adult humans. We've been trying to find a way to help people with drug addiction, and we got introduced to biohacking. We're interested in being able to change people's nervous systems either through microwave radiation (https://www.ncbi.nlm.nih.gov/pubmed/1312845), CRISPR (if it can do anything at all), or whatever other means that don't technically need surgical procedures.
>
> Thank you all, Jack.
>
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--
-Nathan

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