Re: [DIYbio] Re: Drug addiction biohacking

Well the bottom line is, we're looking to experiment with switching off the GABA receptor's capacity to allow xenobiotic agonists to bind to them, also looking to do this with things like microwaves. We need to have the capacity to shut off only the parts of things like GABA and NMDA to disallow certain chemicals to be agonists/antagonists for them. This doesn't involve warfare, there are some people who are too addicted for rehab or anything similar to do anything for them. We're looking to go into the nervous system and actually shut off parts of the CNS so that drugs can't do anything to them - and we want a way to reverse the process to reestablish everything after they have recovered. I know this is radical, and I'm not familiar with anyone who's accomplished this, but hopefully this gets some sort of a ball rolling.

On Monday, September 23, 2019 at 2:49:21 PM UTC-4, Chris Santos-Lang wrote:

I am worried that applying biology to drug addiction is like applying nuclear fission to warfare. Drug addiction and war are social problems, not biological or physical problems, so bringing in biology and physics really just escalates the arsenal.

How's about applying science to analyze and correct the social problem?

Best Wishes,

Chris Santos-Lang

On Mon, Sep 23, 2019 at 3:27 AM Darlene Aldente <darlene...@gmail.com> wrote:

Check out D-Cycloserine. a search of "d-cycloserine and addiction" in pub med or google scholar will give you a ton of recent peer reviewed articles. This is an old tuberculosis antibiotic that has been discovered to act on the glutamate receptor int the brain which is central to the neuroplasticity disruption associated with addition. It has shown real results when combined with CBT and the CBT sessions are times with ingestion of the drug. Same method has shown great results for war related PTSD. because the drug increases neuroplasticity, and for other reasons, it has a measurable positive effect on learning (if only I had this drug in college). You Do NOT need to take the full tuberculosis dose, just half. Also, I'm not sure about the duration of treatment.

There is one BIG problem however: the cost. This drug has recently fallen prey to opportunistic "investors."  in 2015 the price of cycloserine increased from $500 for 30 pills to $10,800 Rodelis Therapeutics purchased it. Purdue University, the previous owner, which retained "oversight of the manufacturing operation" intervened and Rodelis returned the drug to an NGO of Purdue University foundation whi8ch now charges $1,050 for 30 capsules. If you discover a way to use the NGO system through wich governments and non-profits obtain the drug for a fraction of the price please let us know!!

On Thursday, September 19, 2019 at 5:40:44 PM UTC-4, jackson parks wrote:

Hello,

Thank you for letting me in. I'm Jack. A friend of mine named Jonathyn recently quit the idea of engaging in CRISPR CAS9 technology because he found out that it can't do anything for adult humans. We've been trying to find a way to help people with drug addiction, and we got introduced to biohacking. We're interested in being able to change people's nervous systems either through microwave radiation (https://www.ncbi.nlm.nih.gov/pubmed/1312845), CRISPR (if it can do anything at all), or whatever other means that don't technically need surgical procedures.

Thank you all, Jack.

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