Re: [DIYbio] COVID related pathology

Its amazing how much we are still learning about how this virus spreads throughout the body and does damage.  I wonder how this will affect disease treatment and if it gives us any new types of therapeutic targets.

On Wed, Jul 1, 2020 at 10:34 AM Abizar Lakdawalla <abizarl@gmail.com> wrote:
Great article in Wash Post on results from autopsies of patients who have died from COVID

"the virus appeared to destroy these cells, which produce platelets, leading to uncontrolled bleeding ... found widespread clotting in many organs ... abnormal clotting in the heart, kidney, liver, as well as the lungs of seven patients, leading the authors to suggest this may be a major cause of the multiple-organ failure in covid-19 patients ... associated with abundance of a rare cell called megakaryocytes, which produce platelets that control clotting, typically exist only in the bone marrow and lungs ... the widespread presence of tiny clots (in brains) was "striking." "If you have one blood clot in the brain, we see that all the time. But what we're seeing is some patients are having multiple strokes in blood vessels that are in two or even three different territories," ... suggest anti-platelet medications, in addition to blood thinners, may be helpful to stem the effects of covid-19.

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