Re: [DIYbio] Blood clot risk due to Corona vaccine

Thank you for your answer drllau,
I think we are just on the threshold of personalized medicine. I did a 23andme test many years ago and am thinking about doing full genome sequencing.
With the 23andme raw data alone, I have an overview of tens of thousands of SNPs. Maybe this will give me some knowledge about whether I might fall into a risk class regarding the occurrence of adverse vaccine reactions.
For the risk of getting a severe corona disease, there are already numerous studies that determine which genetic variants lead to a higher risk on the basis of molecular genetic data.
For example this one:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724655/


drllau schrieb am Sonntag, 4. April 2021 um 05:59:50 UTC+2:
I've heard there's 6-7K "rare" defects (or tendencies to disease) that collectively affect 1 in 17 westerners. It sucks but when the genetic lottery is against you there's not much you can do unless you're a billionaire boomer willing to have your lineage tested as part of any drug trial. There's  still a long long way to go before personalised medicine, organ on a chip and computational metabolics can become a phase IV trial to eliminate such risks.

On Saturday, 3 April 2021 at 08:11:57 UTC+8 matt.e...@gmail.com wrote:
Mike,

Perhaps this article might reveal some effort on this front, and the names of those involved.


Matt

On Apr 2, 2021, at 7:18 PM, 'Mike Petersen' via DIYbio <diy...@googlegroups.com> wrote:

Hello everyone, if you follow the current situation in Europe, you will notice what a mess it is with the Astrazenica vaccine. The cases of sinus vein thrombosis and fatal blood clots have caused it to be partially withdrawn and then reintroduced with restrictions.

There is great debate about not overstating the risk, but of course it is tragic for any individual to die from a fatal vaccine side effect.
Wouldn't it be much more scientific to investigate what factors came together in those affected and led to these effects. What do I gain by referring to the low probability that it could occur in me and relying only on statistics. Wouldn't it be much safer and more scientific to determine the individual risk based on biomarkers (blood values, genetic features, etc.). The question is whether information is available, for example, studies that show commonalities of those affected. Are any of you aware of anything on this?
Thank you,
Mike

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