This reminds me of a post someone dropped a bit over a decade ago - still on my backlog of projects I don't have the spare time and resources for (I think his name started with a B ["Byron" maybe?] but I can't remember for the life of me, Cathel Garvey might know if he's still around) - but you can control oligonucleotides with microfluidic channels which have really basic capacitor setups printed on the walls and just move them around like charged particles after imparting a charge. Once you have that you can just connect them to a vat with pure oligonucleotides, binding agents, etc, and set it up like a binary tree to work your way up from 2 oligonucleotides being fused together to millions or billions or trillions - which at the scale of a microfluidic chip is pretty simple to scale out, you'll just need to write a program to map that stuff out geometrically so you don't waste decades doing it by hand. This of course all requires a sputtering machine, etcher, etc, but it's already proven tech (sorry I don't have the research papers on me, it's been awhile.)
Hi all,I am working on creating an open source chip for oligo synthesis. In order to test it out, I'm in need of an oligo synthesizer (that has a flow cell I can hack to do what I need). Any advice on where to buy a good used one? Or even better, does anyone have an oligo synthesizer on hand they'd be willing to sell?Thanks,Keoni
-- You received this message because you are subscribed to the Google Groups DIYbio group. To post to this group, send email to diybio@googlegroups.com. To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com. For more options, visit this group at https://groups.google.com/d/forum/diybio?hl=en
Learn more at www.diybio.org
---
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To unsubscribe from this group and stop receiving emails from it, send an email to diybio+unsubscribe@googlegroups.com.
To view this discussion on the web visit https://groups.google.com/d/msgid/diybio/4adbb385-256b-42cc-b039-348959cb8bd0n%40googlegroups.com.
0 comments:
Post a Comment