Biology is nanotechnology using nanomachines; therefore it is possible to create CAD systems which create compatible and/or replacement nanomachines to either interface with existing biology, or to simply create a New Biology. The present limitation is that the design rules of the nanotechnology are not well understood or replicable, thus leading to a "design by trial & error approach" rather than a "design by known rules" approach, and that is the fundamental weakness in biology and biological engineering today. Today's methods, BioBricks or other, are tremendously overhyped and the "design by trial & error" methods have a failure rate of near 100% when scaled beyond the trivial.
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