Math and bio?

I've been getting into mathematical models lately, and have noticed
that many of these models don't really take into account the signaling
complexities of biology. To this end I was wondering if anyone could
point me in the direction of a general equation, etc. that models
either the process of selecting a gene to be transcribed in a cell
(all of the different transcription affinity and negating factors), or
of quantifying the amount of mobilization of an enzyme which is
activated through a complex enzyme cascade. A name of an equation or
modeling style would be enough to get me started, I haven't been able
to find much of anything beyond the idea of the stochastic general
equation and markov, non-markov type equations. To put a context to
this broad question, I'm interested in the ligand gated g protein
receptor cascades in neurons, and the control of receptor populations/
synapse modulation (synaptic placticity) at a genetic (or at any
other) level. Having looked over a goodly amount of articles it seems
to me like this has been mainly studied at a qualitative level, much
less so at a specific quantitative level. Sorry to pollute the board
with my neuroscience again :P, but I think this would be interesting
to the slightly higher level genetics researchers here as well. :)
Thanks for any information in advance, and I apologize for my
ignorance if this is a commonly understood topic, I don't really have
access to a professor of, well, anything. :)

Jonathan Nesser
diybioandneurosci.blogspot.com

--
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To post to this group, send email to diybio@googlegroups.com.
To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com.
For more options, visit this group at http://groups.google.com/group/diybio?hl=en.

  • Digg
  • Del.icio.us
  • StumbleUpon
  • Reddit
  • RSS

0 comments:

Post a Comment