[DIYbio] Re: Designer Probiotics. Anyone interested in this?

I'm really interested in the idea of modified got bacteria. I don't
really care about the obesity issue compared to overall health but I
think the problems of integrating something new into such a complex
environment is a shared problem. I'm not in your area but can pursue
this idea at LA biohackers.

Romie


On Feb 28, 9:11 am, naiverahim <rahim.ba...@gmail.com> wrote:
> Recently I've been really interested in the idea of designing 'good
> bacteria' to do even more good for the gut. I've conceived of a way to
> design Bifidobacteria (with 2 genes --> 2 enzymes) to destroy fat
> before it's absorbed into the body or excreted in feces. This would be
> a really cool designer probiotics that would benefit so many people,
> particularly those on high fat diets (obesity). Taking Bifidobacteria
> longum as a supplement has been shown to resist diet-induced obesity
> and mitigate metabolic syndrome in rodents but of course the effects
> are marginal. My goal is to shift metabolism towards fat degradation
> in these designer probiotics to deliver appreciable benefits. It'd be
> nice to have someone to bounce ideas with. Let me know if your
> interested so I can send you some good literature on this.
>
> I'll be doing much of the work between City College and GenSpace in
> Brooklyn. Anyone in the area?
>
> Bam!,
> Rahim

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