Re: Radio opaque biomolecule?

Oh my GOD such a small spark is bringing so many ideas and
suggestions...
I feel very happy to so many responses to my query...
Really this group is very powerful...
i really believe that miracles happen when may brains combine...
Thank you everyone for your useful suggestions....

On Jan 3, 6:30 am, CoryG <c...@geesaman.com> wrote:
> If you are looking at imaging methods, I'd suggest pursuing phased
> arrays.  You can get sub-wavelength resolution out of the phasing and
> depending how it's made (freq-phasing, phase-angle phasing, amplitude
> phasing, etc) can get the ability to view/control variable size
> objects instead of having to focus on a single target molecule.
> Phased arrays are going to be huge when they are properly utilized
> within the medical industry (with what would probably be a
> supercomputer today running one) - but there seems to be little work
> on it at the moment, you can definitely see the start in dumb-rf (for
> lack of a better term) forms of cancer treatment utilizing metallic
> nano-particles and what is more or less an induction coil to burn out
> the cells.  With enough precision (ie: more nodes, more computing
> power, vastly greater cost) you could image and manipulate living
> cells in real time (conductivity of ion pathways, affinity for
> particular chemical reactions in a region, heating/cooling, etc).  Of
> course, if you are trying to get something done with it in the
> immediate future, phased arrays probably aren't the way to go - I
> started on one about a year ago and got side tracked on building new
> super-capacitors (having done so because I found a way to make better
> ones while trying to cut the costs of a 210KVA power supply to wellunder the $10-$15k it would cost just in iron if I were to hand-make
> the transformers).  In a DIY sense, there's a lot to be done to get
> phased arrays into an attainable realm, mainly in power supplies and
> broadband phase-shifters (everything else is relatively cheap per
> component, but increases in cost with the number of nodes).  Didn't
> mean to get too off-topic here, but RF is a pretty cool subject - it's
> kind of sad the greatest modern use of it is in telecommunication.
>
> On Jan 2, 6:55 pm, Nathan McCorkle <nmz...@gmail.com> wrote:
>
>
>
>
>
>
>
> > On Mon, Jan 2, 2012 at 6:38 PM, John Griessen <j...@industromatic.com> wrote:
> > > On 01/02/2012 12:41 PM, Simon Quellen Field wrote:
>
> > >> Suppose we made a strongly polar molecule that was fairly large in
> > >> comparison
> > >> to other strongly polarized molecules in the body (a small peptide is
> > >> large in
> > >> comparison to water, for example). We build it so that it changes its
> > >> length in
> > >> response to something we want to measure (some gene expression or siRNA,
> > >> or
> > >> maybe just oxygen levels). Now it will resonate at a different radio
> > >> frequency
> > >> when the levels of that target change.
>
> > >> We already do this with light. An acid-base indicator is a large molecule
> > >> that
> > >> resonates at a particular frequency (say that of blue light) in a basic
> > >> solution,
> > >> but resonates at a different frequency (red light) in an acid. Making the
> > >> molecule
> > >> larger shifts the frequency lower
>
> > > Good thinking Simon.  Like it.  Would be nice to open hardware something
> > > like that
> > > because it is the classic instrument that makes something invisible become
> > > visible.
>
> > > And it seems novel to me...
>
> > We may have touched on this before, but this seems very close to
> > bio-telecommunication...
>
> > > --
> > > You received this message because you are subscribed to the Google Groups
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> > > To post to this group, send email to diybio@googlegroups.com.
> > > To unsubscribe from this group, send email to
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>
> > --
> > Nathan McCorkle
> > Rochester Institute of Technology
> > College of Science, Biotechnology/Bioinformatics

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