Re: Radio opaque biomolecule?

It heats the water because the frequency matches the resonant

frequency of the water molecules. Using a different frequency
targets different molecules.

MRI imaging is done using radio waves. Diffraction is only an issue
in the far field. Near field imaging is not limited by diffraction, and
in fact we have scanning near field optical microscopes that image things far
below the wavelength of light. MRI imaging as fine as 90 nm is being
done using scanning techniques in the near field, and IBM has done 3D
MRI imaging down to 4 nm. All with radio waves.

Cell Impedance Spectroscopy is another DIY accessible technology that
uses easily generated frequencies.

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On Mon, Jan 2, 2012 at 11:08 AM, Jelmer Cnossen <j.cnossen@gmail.com> wrote:



On Mon, Jan 2, 2012 at 7:41 PM, Simon Quellen Field <sfield@scitoys.com> wrote:
Well, not quite.

My microwave oven put out radio waves, and it seems to have an effect
on quite a bit of biological material.
:-)

I fully trust your microwave, but it heats because the food has water in it :) 
It will be hard to see anything interesting biologically, because all there is soo much more water in biological tissue than you can compensate with using high proteins concentration.

Also, spectroscopy on radio wavelengths, possibly maybe. But imaging on cell scale is definitely a no go because you're diffraction limited to the radio wavelengths.



On Mon, Jan 2, 2012 at 6:11 AM, Jelmer Cnossen <j.cnossen@gmail.com> wrote:

It largely depends on the wavelength whether this is useful. According to wikipedia, the smallest wavelength that still counts as "radio waves" is 1 millimeter, so you can only see stuff bigger than that. That rules out any subcellular structures. And at this size, you can just as well put the thing in MRI (Not really diybio though ;) )
Next to that, the reason that radio waves are harmless is probably because no biological structures are organised enough on that wavelength scale to take up energy from it.

On Mon, Jan 2, 2012 at 7:40 AM, Veera <drveerammc@gmail.com> wrote:
Recently i had some ideas about radioimaging gene expression. There
are many ways to study gene expression like using flourescent protien
tags. but all those requires sacrificing the animal for taking tissue
sections for immuno histochemistry. so i was searching some concepts
for visualizing gene expression within specific tissues inside the
body by some imaging techniques.Incidentally i came across bio
activated contrast agents.You can see that in this link <link>http://
www.nibib.nih.gov/HealthEdu/eAdvances/23Oct06<link>. But instead of
using contrast agent i'm just curious to know is there anything like
any protien or any biomolecule which is naturally radio opaque whose
gene can be sandwiched with the promoter of the gene of interest and
so we can image the the tissue and study the gene expression without
killing the animal.....

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