Re: [DIYbio] 3D printing medical devices

On Fri, Sep 28, 2012 at 12:34 PM, Nathan McCorkle <nmz787@gmail.com> wrote:
> As far as I remember, the main concern is getting a piezo electric
> print head over a heating type, where the heat causes the ink to
> expand and squirt out. This cooks cells and proteins.

Speaking as someone who actually read certain articles that someone
else here says I completely missed the point of, the problem seems
instead to be this:

"The big challenge in understanding how to grow large artificial
tissue is how to keep all the cells alive in these engineered tissues,
because when you put a lot of cells together, they end up taking
nutrients and oxygen from neighbouring cells and end up suffocating
and dying."

http://www.bbc.com/news/technology-18677627

It seems that even the thinnest cellular layer you can "print" is
still "a lot of cells together" -- smothering and starving each other.
Presumably, the printed sugar conduits (whose walls dissolve) need
only last long enough to get the cells they are hosting some
nutrients, i.e., a kind of artificial angiogenesis that'll do until
the real thing comes along.

Wow, I almost sounded like a biohacker there! (IRL: I needed to do a
reverse-lookup on google to get "angiogenesis". So actually not.)

Regards,
Michael Turner
Project Persephone
1-25-33 Takadanobaba
Shinjuku-ku Tokyo 169-0075
(+81) 90-5203-8682
turner@projectpersephone.org
http://www.projectpersephone.org/

"Love does not consist in gazing at each other, but in looking outward
together in the same direction." -- Antoine de Saint-Exupéry


> Biocurious has a project wiki for their bioprinter project:
> http://biocuriousmembers.pbworks.com/w/page/48912717/Bioprinter%20Project
>
> On Thu, Sep 27, 2012 at 6:40 PM, William Heath <wgheath@gmail.com> wrote:
>> Hi All,
>>
>> I have been very interested in doing bio printing. I tried to get an old hp
>> deskjet printer and make it print a jello like substance but couldn't even
>> do that. I am completely frustrated with how to do this. Can anyone give
>> me some real help to figure out how to do this for a diybio person? I am
>> trying to think of what would be a good approach to developing the diybio
>> bio printer. My idea was that I would start with trying to print a jello
>> like gel with different colors in the wells to "test" that it is working.
>> After I complete that task I would then move on to perhaps printing some
>> plant cells or something. I would then like to print cells that are not
>> dangerous to work with like human cells. I am curious are bone cells
>> considered safe? What cells are appropriate for bio printing that would be
>> safe? I keep looking at the makerbot and thinking in my mind, can't this be
>> adapted to bio printing? The only thing I see missing is that the platform
>> needs to move up and down that is being printed on. Isn't that all that is
>> missing? I guess the resolution may not be high enough either. Anyway, I
>> would love to get a simple working bio printer up and working, help me ob1,
>> YOUR MY ONLY HOPE! :>
>>
>> -Tim
>>
>> P.S.
>>
>> I turn cell phones into robots. I am very familiar with arduinos, laser
>> printing, serial communication. You can see my latest robot here:
>>
>> http://www.youtube.com/watch?v=E_q5WD3dTkE
>>
>>
>> On Wed, Sep 26, 2012 at 12:12 PM, kingjacob <kingjacob@gmail.com> wrote:
>>>
>>> You can print in titanium using Direct Metal Laser Sintering. You can
>>> pretty much print with any material you can turn into a powder or resin. A
>>> friend of mine (papers below) even used a NaCl mixture to 3D print tissue
>>> scaffolding.
>>>
>>> Computer-aided tissue engineering: benefiting from the control over
>>> scaffold micro-architecture.
>>>
>>> http://www.ncbi.nlm.nih.gov/pubmed/22692601
>>>
>>> Scaffold pore space modulation through intelligent design of dissolvable
>>> microparticles.
>>>
>>> http://www.ncbi.nlm.nih.gov/pubmed/22692605
>>>
>>> Computer-aided tissue engineering of a human vertebral body.
>>>
>>> http://www.ncbi.nlm.nih.gov/pubmed/16240082
>>>
>>> On Wed, Sep 26, 2012 at 4:45 PM, Nathan McCorkle <nmz787@gmail.com> wrote:
>>>>
>>>> I've never heard anyone on here discussing printable hip
>>>> replacements... it sounds like a bad idea anyway, seeing as how poor
>>>> 3D printer plastics fair in strength. Most joint replacements are made
>>>> of titanium, etc... Who put that in there?
>>>>
>>>> It also has really old info scattered throughout, and doesn't mention
>>>> anything of the years of FBI interaction we've had
>>>>
>>>> On Tue, Sep 25, 2012 at 9:02 PM, Bryan Bishop <kanzure@gmail.com> wrote:
>>>> > The wikipedia articles are still awful.
>>>> >
>>>> > http://en.wikipedia.org/wiki/Biohacking
>>>> > http://en.wikipedia.org/wiki/DIYbio
>>>> > http://en.wikipedia.org/wiki/Biopunk
>>>> >
>>>> > At least that last one is somewhat less awful. Anyone want to take
>>>> > cleanup
>>>> > duty?
>>>> >
>>>> > - Bryan
>>>> > http://heybryan.org/
>>>> > 1 512 203 0507
>>>> >
>>>> > --
>>>> > You received this message because you are subscribed to the Google
>>>> > Groups
>>>> > "DIYbio" group.
>>>> > To post to this group, send email to diybio@googlegroups.com.
>>>> > To unsubscribe from this group, send email to
>>>> > diybio+unsubscribe@googlegroups.com.
>>>> > For more options, visit https://groups.google.com/groups/opt_out.
>>>> >
>>>> >
>>>>
>>>>
>>>>
>>>> --
>>>> Nathan McCorkle
>>>> Rochester Institute of Technology
>>>> College of Science, Biotechnology/Bioinformatics
>>>>
>>>> --
>>>> You received this message because you are subscribed to the Google Groups
>>>> "DIYbio" group.
>>>> To post to this group, send email to diybio@googlegroups.com.
>>>> To unsubscribe from this group, send email to
>>>> diybio+unsubscribe@googlegroups.com.
>>>> For more options, visit https://groups.google.com/groups/opt_out.
>>>>
>>>>
>>>
>>>
>>>
>>> --
>>> Cheers,
>>> Jacob Shiach
>>> editor-in-chief: Citizen Science Quarterly
>>> founder: Brightwork CoResearch
>>> twitter: @jacobshiach
>>>
>>> --
>>> You received this message because you are subscribed to the Google Groups
>>> "DIYbio" group.
>>> To post to this group, send email to diybio@googlegroups.com.
>>> To unsubscribe from this group, send email to
>>> diybio+unsubscribe@googlegroups.com.
>>> For more options, visit https://groups.google.com/groups/opt_out.
>>>
>>>
>>
>>
>> --
>> You received this message because you are subscribed to the Google Groups
>> "DIYbio" group.
>> To post to this group, send email to diybio@googlegroups.com.
>> To unsubscribe from this group, send email to
>> diybio+unsubscribe@googlegroups.com.
>> For more options, visit https://groups.google.com/groups/opt_out.
>>
>>
>
>
>
> --
> Nathan McCorkle
> Rochester Institute of Technology
> College of Science, Biotechnology/Bioinformatics
>
> --
> You received this message because you are subscribed to the Google Groups "DIYbio" group.
> To post to this group, send email to diybio@googlegroups.com.
> To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com.
> For more options, visit https://groups.google.com/groups/opt_out.
>
>

--
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To post to this group, send email to diybio@googlegroups.com.
To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com.
For more options, visit https://groups.google.com/groups/opt_out.