Re: [DIYbio] surface plasmon resonance

You can use some kind of polymer emulsion to fix membrane proteins on
the surface, then wash with a chemical library to detect binding.

Yeah, just wondering how to drive down costs...

On 19 November 2012 22:59, Nathan McCorkle <nmz787@gmail.com> wrote:
> i've seen some stuff on SPR detectors before, but I'm pretty sure you still
> need the surface to be functionalized, and this would detect binding, so not
> sure how you would use SPR to develop mito transporter inhibitors
>
> cost is expensive (several thousands to hundreds of thousands, depending on
> production of developed designs vs research), since this is still
> predominantly big-lab big-money research
>
>
> On Mon, Nov 19, 2012 at 2:30 PM, Dan Bolser <dan.bolser@gmail.com> wrote:
>>
>> Can anyone build me one of these:
>>
>> http://www.biacore.com/lifesciences/technology/introduction/following_interaction/index.html
>>
>> What cost?
>>
>> I want to develop specific inbibitors of mitochondrial transporters.
>>
>>
>> kthxbi
>>
>> --
>> -- You received this message because you are subscribed to the Google
>> Groups DIYbio group. To post to this group, send email to
>> diybio@googlegroups.com. To unsubscribe from this group, send email to
>> diybio+unsubscribe@googlegroups.com. For more options, visit this group at
>> https://groups.google.com/d/forum/diybio?hl=en
>> Learn more at www.diybio.org
>> ---
>> You received this message because you are subscribed to the Google Groups
>> "DIYbio" group.
>> To post to this group, send email to diybio@googlegroups.com.
>> To unsubscribe from this group, send email to
>> diybio+unsubscribe@googlegroups.com.
>> Visit this group at http://groups.google.com/group/diybio?hl=en.
>> To view this discussion on the web visit
>> https://groups.google.com/d/msg/diybio/-/eKYYj-F9mgAJ.
>> For more options, visit https://groups.google.com/groups/opt_out.
>>
>>
>
>
>
>
> --
> -Nathan
>
> --
> -- You received this message because you are subscribed to the Google Groups
> DIYbio group. To post to this group, send email to diybio@googlegroups.com.
> To unsubscribe from this group, send email to
> diybio+unsubscribe@googlegroups.com. For more options, visit this group at
> https://groups.google.com/d/forum/diybio?hl=en
> Learn more at www.diybio.org
> ---
> You received this message because you are subscribed to the Google Groups
> "DIYbio" group.
> To post to this group, send email to diybio@googlegroups.com.
> To unsubscribe from this group, send email to
> diybio+unsubscribe@googlegroups.com.
> Visit this group at http://groups.google.com/group/diybio?hl=en.
> For more options, visit https://groups.google.com/groups/opt_out.
>
>

--
-- You received this message because you are subscribed to the Google Groups DIYbio group. To post to this group, send email to diybio@googlegroups.com. To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com. For more options, visit this group at https://groups.google.com/d/forum/diybio?hl=en
Learn more at www.diybio.org
---
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To post to this group, send email to diybio@googlegroups.com.
To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com.
Visit this group at http://groups.google.com/group/diybio?hl=en.
For more options, visit https://groups.google.com/groups/opt_out.