On Wednesday, December 12, 2012 8:51:27 PM UTC-8, Bryan Bishop wrote:
From: Luke Weston <reindeer...@gmail.com>
- It is likely that most "DIY-bio" activities in Australia involving recombinant DNA, if any, are either exempt or NLRD. Dealings in a higher-risk category are likely to be rare to nonexistent. I would have a pretty good suspicion that nobody in the DIY-bio community would ever be likely to have any interest in any activity with GMOs or pathogens requiring a laboratory designed for (and regulated/approved for) PC2-or-greater containment.
If the PC categories are at all similar to the BioSafety Levels (BSL) here in the US, then yes, there are definitely DIYbio activities that strictly speaking would require a BSL-2 facility. That includes any time you isolate something from an environmental sample (e.g. isolating bioluminescent bacteria from fish!) or when you're working with human samples.
Again, strictly speaking, in a BSL-1 laboratory, you are only supposed to work with organisms that you know to be harmless. That would rule out any kind of environmental samples or microbiome analysis. I've definitely seen academic labs in the US play fast-and-loose with those rules as well though. But depending on how paranoid your local government is, it could be used as an excuse to crack down on certain DIYbio activities.
- It is completely implausible that anybody in the DIYBio community or hackerspace or similar communities would have any interest in any dealings with any of the high-risk pathogens or biotoxins on the SSBA list
How about, for example, synthesizing entirely harmless enzyme genes that just happen to be found in a pathogen? That tends to be a grey area where you normally need some review board to sign off on its safety in an academic setting.
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