Re: [DIYbio] Re: Oxidative stress: Less harmful than suspected?

Interesting!

Yeah, I imagine a metabolic pathway where a mammal just does anoxic metabolism. But the problem is, aerob metabolism gives you by far more energy. And, they would then produce acids, which they have to get rid of. The acids may have an effect on lifespan too. Maybe neutralizing the acids could work by producing bases in parallel? Or exporting the acids in a natural manner.



On Mon, Dec 10, 2012 at 7:44 PM, Daniel C. <dcrookston@gmail.com> wrote:
On Mon, Dec 10, 2012 at 9:34 AM, Mega <masterstorm123@gmail.com> wrote:
> What would be truely interesting, is to make a mammal live without oxygen
> and then compare the lifespan/ health in the same age to another oxygen
> breathing one. But this won't be easy, by far not, I suspect...

This experiment is currently being conducted all over the planet -
mammals that live at sea level get much more oxygen than those that
live in, say, the Himalayas.  I only know of one mortality study where
altitude came up as a factor:
http://www.sciencedaily.com/releases/2011/01/110113131436.htm but I'd
be interested in learning more.

Also, if you literally meant without *any* oxygen, then that really
would be a challenge.

-Dan

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