I'd say people have always wanted to learn new things about nature. Think of the old greek natural philosophers. Aristotle wandering through the fields and wondering what that plant may be the cure for. Or how stuff works. Or how it is formed. Curioity.
Another goal is that we finally are able to do something great, that lasts for a long time. Take creating glowing plants :)
Or smelly bacteria (smelly in the positive sense, such as the banana-odour bacteria from IGEM).
Or insert artemisin genes into a easy-to-cultivate plant to be able to cure malaria cheaply (you potentially could help the less developed contriies with it. That's kind of compassion, just on a higher level than just giving them clean water)
There surely are many good reasons for doing diy bio!
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