Re: [DIYbio] DIY Microfluidics + Parasitology Diagnostics



On Friday, January 25, 2013 12:18:55 AM UTC-6, Marc Dusseiller wrote:



we tried making our devices with our homebuilt laser cutter. works very nice. but the resolution is limited to approx 100µm. which is cool for some cell culture and flow devices. for sorting, squeezing single cell not enough.


Looks like you have sufficient resolution to build a gene synthesizer. Problem is, the chemicals involved in DNA synthesis might do a number on PDMS based devices. So you'll have to use something more solvent resistant like the elastomer PFPE, which happens to be processed in a similar manner. Though you might need an inert atmosphere to fabricate them though.


On a lighter note, you also have sufficient resolution to make the sound amplification chip for this totally steampunk fluidic gramophone, though you'll need to use resin that won't deform like PDSM. Polyester resin should do the trick. It is a high reynolds number device, so it'll be interesting to see(hear?) how well the process works.

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