Re: [DIYbio] Human enhancement

Hi Tom,
yes, the FDA have been dancing around the topic for more than a decade.
Hplus magazine (from 2008) discusses legal ramifications in various jurisdictions - http://hplusbiopolitics.wordpress.com/2008/03/02/those-with-germline-modified-mitochondria-walk-among-us/
They link also to an earlier article, the (not-so-subtle) distinctions between nuclear transfer and transfer of ooplasmic material as a means of achieving this are also covered.
Professor Chinnery of Wellcome Trust Centre for Mitochondrial Research was in the news back in 2008 http://news.bbc.co.uk/2/hi/7227861.stm
http://www.newcastle-mitochondria.com/portfolio/professor-patrick-chinnery/
Jacques Cohens' group published their work in Lancet in 1997;
"Birth of infant after transfer of anucleate donor oocyte cytoplasm into recipient eggs."  http://www.ncbi.nlm.nih.gov/pubmed/9250192
As those working in the area are wary of falling afoul of regulations on germline engineering, my understanding is that it had been presented as a happy, though unintended, consequence of cytoplasm transfer in an experimental fertility treatment.
Remains to be seen where we go from here..
Steve


On Sunday, 23 March 2014 17:21:55 UTC, Tom Randall wrote:

On Saturday, March 22, 2014 2:51:38 AM UTC-4, scriptdoc wrote:

Hello Mega,

I am a movie script writer. I also belong to the diybio forum.  I would love to chat with you at your earliest avaiability to discuss this issue with you at length.

I think that 3 parent embryos sound very high concept and futuristic. I would love to envision with you a story that may if done well....and shown at festivals.....push the envelope for further developments.

If your interested in contacting me please write to me directly at kthrn...@gmail.com 

Thank you,

Kate

 Not so futuristic anymore, more of a regulatory issue, at least in one case, replacing the mitochondrial genome.

http://www.cnn.com/2014/02/26/health/ivf-mitochondria/