You can do the same search at the NCBI, too.
On Wednesday, August 6, 2014 6:27:00 AM UTC-7, Mega [Andreas Stuermer] wrote:
-- Searching with "berberine" finds 61 structures, both proteins (mostly transcriptional regulators) and DNA.
http://www.ncbi.nlm.nih.gov/structure/?term=berberine
PDB is nice, but I think the NCBI is a little easier to use.
On Wednesday, August 6, 2014 6:27:00 AM UTC-7, Mega [Andreas Stuermer] wrote:
Hi!Could use some help with the following:One mode of action is that berberine and derivates activate cbl-ubiquitin ligase. Now I was told to identify structures where berberine binds to. So maybe to cbl, or some upstream protein.
I don't know of any bioinformatic tool that is advanced enough to solve this. Does anyone know of one?Best,Andreas
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