Re: [DIYbio] Comprehensive Genome Project or Feasibility Thereof

Did some more research on this if anyone is interested.

Total Mbp to sequence (only cellular life): 10,031,623,401 - 14,211,856,834*
Total cost at current sequencing rate per Mbp: $501,581,170.00 - $710,592,841.70*
Total cost at lowest known sequencing rate per Mbp (a few months ago): $401,264,936.00 - $568,474,273.30*
*wide ranges are the result of wide estimates primarily in archaea and bacteria

Considering the Human Genome Project cost $2,700,000,000 it seems feasible given the massive price drop in sequencing (at least for cellular life - viroids are too difficult to estimate total numbers of)

Sources:
  • Data from the previous link compiled down with a script to average Mbp/subgroup.
  • http://www.genome.gov/sequencingcosts/ for the cost to sequence (about $0.05 / Mbp [up from $0.04 / Mbp earleir in the year])
  • Sources around the web (mostly Wikipedia) for total numbers of cellular life by subgroup where availble and group or kingdom otherwise.

On Thursday, November 20, 2014 8:51:03 AM UTC-5, Cory Geesaman wrote:
Yes.

On Thursday, November 20, 2014 8:46:15 AM UTC-5, Cathal (Phone) wrote:
To be clear, do you mean "is anyone just trying to generate a firehose of unprocessed sequence data for every living thing known to man"?

On 20 November 2014 13:36:54 GMT+00:00, Cory Geesaman <co...@geesaman.com> wrote:
I've been looking around with little success so figured I'd ask here.  Does anyone know of a genome sequencing project aimed at mapping genomes of all known species?  If none exist, how feasible would it be to get something like it going with modern technologies like Ion Torrent and maybe just refine the technique as you go to get something that could be used for analytics when trying to design a synthetic organism?  The most comprehensive list I've found thus far is http://www.ncbi.nlm.nih.gov/genome/browse/ and it's pretty lacking (10,816 genomes mapped, only 1,149 in all of Eukaryota, 423 Animals, 9 Reptiles, etc).  Anyone have insight into the operational costs of a project aimed at nothing more than mapping genomes (assume sample collection is free and just limit it to the actual equipment and labwork).


--
Sent from my Android device with K-9 Mail. Please excuse my brevity.

--
-- You received this message because you are subscribed to the Google Groups DIYbio group. To post to this group, send email to diybio@googlegroups.com. To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com. For more options, visit this group at https://groups.google.com/d/forum/diybio?hl=en
Learn more at www.diybio.org
---
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To unsubscribe from this group and stop receiving emails from it, send an email to diybio+unsubscribe@googlegroups.com.
To post to this group, send email to diybio@googlegroups.com.
Visit this group at http://groups.google.com/group/diybio.
To view this discussion on the web visit https://groups.google.com/d/msgid/diybio/e1abd8b2-c248-4140-9b05-c2543fa216b5%40googlegroups.com.
For more options, visit https://groups.google.com/d/optout.

  • Digg
  • Del.icio.us
  • StumbleUpon
  • Reddit
  • RSS

0 comments:

Post a Comment