Re: [DIYbio] Surface Plasmon Resonance

I have no idea what that machine does, but ask companies with millions of dollars if they'd buy it, not poor people like us.

As a story, someone I went to college with works at an antibodies company.  She and her boyfriend designed and welded a simple piece of metal that let's you stack western blot plates on top of one another on the orbital shaker.

She showed it to the higher ups and they wrote her a check for $10,000 and bought 100 of them..

Find a problem a company has, and fix it.  I personally don't know any DIYBio person who has a plasmond resonance issue, but there might be businesses out there that do.

On Fri, Jan 23, 2015 at 3:14 PM, Daniel Glenn <daniel....@gmail.com> wrote:

I was wondering if their would be interest in an affordable surface plasmon resonance bio-assay sensor?

Surface plasmon resonance can be used as a method to detect antibody-antigen (and other) reactions directly with an optoelectronic sensor. Biacore and others make very expensive instruments that read 96-well plates, but I'm talking about something that reads samples one at a time and doesn't cost $33,000+.

It can be used to perform the same type of assays that occur in Western blot and ELISA without attaching tags, because the probe molecule is immobilized chemically on the surface of the optics with chemistry. Would those type of assays be useful to the general DIYbio community?

Do you think that there would be interest in such a device for the more general citizen-science community if test kits for things like Salmonella or Dengue that anyone with reasonable skills and training could use were developed?

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