Re: [DIYbio] Completely new to DIY gene therapy

DIY Gene Therapy is not, to my knowledge, a "thing" right now, nor
should it be.

As someone who studied nonviral integrative gene therapy several years
back for cancer therapeutic uses, I can tell you that there is no clear
consensus on how to efficiently transfect DNA into live tissue without
incurring a *significant* risk of inducing either cancer or a
catastrophic immune backlash. There have been gene therapy trials that
ended in the sudden deaths of participants due to unforeseen cytokine
storms that *did not occur in prior animal trials*.

Gene therapy is a potentially amazing medical technology, but it was
invented and first trialled over a decade ago, and is not yet a
recommended or permitted therapy for anything that I am aware of, and
the primary reason is that it is not, at all, safe.

I strongly recommend directing your interest in genetics towards one of
the many alternative courses of DIY research and leave gene therapy to
specialists with a strong medicine or immunology background.

On 26/03/15 20:36, Elodie Hart wrote:
> Hello, all. I am completely new and know almost nothing about diy
> gene therapy, but I know I want to get involved in it. Can you please
> suggest some books that are about how to get started in gene therapy
> that are comprehensible to the beginnner? Thank you.
>

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