[DIYbio] Re: Looking for partner or group for DIY TPE

So far here is what i have surmised. The amount of blood taken during a donation varies by donation type, your height and weight, and the donation center. Donations are not supposed to exceed 15% of total blood volume but can be twice that for plasma depending on the individual donor for plasma. when you donate whole blood, the 1 pint or about 1/2 liter taken includes all components. if 60% is plasma that's  262 ML 7.8% of your plasma. When you donate plasma, the pint taken is all plasma so that's 15% of your plasma becasue the other blood components are re-infused.  One reason more total volume can be taken with plasma vs whole blood is that with whole blood there is no volume replacement whereas with plasmapheresis the volume of plasma taken is replaced with saline. So depending on the blood collection center you can ask to donate up to a liter of plasma which is about 30% of your plasma. that starts to approach the promised land.

But wait there's more! Whole blood donations can't be more frequent than once every 4-6 weeks or even longer for some places. But you can donate plasma once every 7-10 days. So in 7 days with two donations you could get very close to the mice in the experiment. The only thing that sucks is getting so much anticoagulant  infused.


On Sunday, June 28, 2020 at 5:36:57 PM UTC-4 Gary Dale wrote:

So, how is the Conboy NBE or TPE any different than just donateing blood or just plasma? Seems to me it's exactly the same except the Conboy's have discovered a NEW Anti Aging benefit. That of flushing out years of accumulated garbage (maybe broken components that the liver/kidneys can't filter out?). You don't replace 50% of your plasma at once but donating 1 pint of blood with 8 weeks between donations should add up :-)


On Saturday, June 27, 2020 at 12:42:46 AM UTC-5, Frank wrote:
Recent published experiments like the one below from UC Berkeley, demonstrate multi-system rejuvenation from an existing widely available procedure, therapeutic plasma exchange TPE.  This is quite exciting and the paper is well worth reviewing. I am interested in begin able to perform TPE on myself with someone's help. If you are interested please let me know.





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