Re: [DIYbio] Re: Covid-19 superspreaders

" Contrary to the previous reply insisting, "the nose is a fragile area,
don't tamper there, you can't optimize it," in fact Hindus have been
rinsing and sticking things up their nose for thousands of years (go try
nostril flossing on your own, hint, don't use minty floss). "


When you live in a city where the concentration of airborne particulate matter at 2.5 microns is so high you can't see farther than a 1/2 mile, then, yes, perhaps you need to wash out your nose. Go to Kerbala and watch some roadside dentistry, or surgery on-demand for cash. Whats the rate of medical malpractice suits? Or do they just run the unliscenced medical technicians out of town via a mob with sticks? The Hindus never conquered the world, did they? Not being facetious. You are engaging in fallacious reasoning (appeal to naturalism or tradition) to justify experimenting with putting stuff in your nose and I salute you. You're an experimenter and an explorer. You will not find scientific support for this endeavor. Did a cursory look- found this: "A recent meta-analysis of 10 controlled trials taken from a review of 11,500 studies included more than 400 allergic rhinitis patients [7]. Regular saline irrigation in adults and children improved nasal symptomatology in 35% of cases and quality of life in 30%" That is not great results. Having a hard time finding efficacy data for studies on the Indian subcontinent.. hehe. I am fully confident going "all-in" against your theory, having experimented with the technique myself- I concluded it was doing more harm than good. Also a Yoga expert. Yoga is about 50% certified bull-crap.  Save yourself some time, or, not, and good luck blazing that trail up your nose and don't say you weren't fairly warned. 
On Wednesday, December 30, 2020 at 12:01:18 PM UTC-8 jnc...@gmail.com wrote:
This could probably be tackled ("solved") as a bioinformatics problem if you can find and connect the right databases between covid and demographics. 

Large, specific populations of people in the world use saline rinses on a daily basis.  Hindus(*) in India for example will use a neti pot as religious practice to flush their noses (bioinformatics sample populations of 100M+) with arbitrary water quality and locally sourced salt, i.e. dirty ingredients.  Yoga practitioners or new-agey types in America also use a neti pot often with pre-measured saline mix packets.  Correlate that population against covid logs.

Contrary to the previous reply insisting, "the nose is a fragile area, don't tamper there, you can't optimize it," in fact Hindus have been rinsing and sticking things up their nose for thousands of years (go try nostril flossing on your own, hint, don't use minty floss).


(*) I use the term Hindus very generally, it is a broad population with broad set of beliefs & practices.

On Monday, December 21, 2020 at 2:36:55 AM UTC-8 loopd...@gmail.com wrote:
Hi,
@ Tom
I wrote to some infectious desease experts and virologists.  Perhaps they already have evident knowledge about the effect of salt on Sars-CoV-2. Lets see what happens. greetings
@ J Boogie
I wrote "nosespray, for example".  You can also garglin or inhale the NaCI solution. I just thought of a practical application for everyday life, which is also able to reduce sneezing and nasal congestion (see "study of Fluid Dynamics..." in my mail above). For hygienic reasons and in order not to disturb our complex system too much, I thought of a normal, isotonized seawater spray that you can buy in pharmacies or supermarkets.  It is approved for permanent use and some allergy sufferers use it for a longer period of time.  Personally, therefore, I don't think that it would be extremely dangerous to use.  But who knows, maybe yes?  I will check again.
Thank you very much.
Jochen

j boogie <justin...@gmail.com> schrieb am Sa., 19. Dez. 2020, 20:37:
The problem is the anatomy of the upper respiratory tract. The nose is kind of a "drain" at the low point. The interior is very complex with a large surface area.  Lets assume you are driving saltwater, saline, or whatever "up" into your respiratory tract. Now you may have possibly transported a virus that is capable of attacking your cells way up in these labyrinthine folds which are very close to the brain. There is an old medical shorthand for this area, its called "the triangle of death", from the corners of the mouth to the bridge of the nose. Deaths have occurred from users of saline irrigation, then transporting waterborne amoebas up there, that otherwise exist in municipal water systems, and don't cause problems because they aren't transported into these areas. This area is NOT designed to be tampered with. If the human body had an area that should be stamped with "no user serviceable parts" it is this area. You cannot optimize this system. It is a diverse ecosystem of immune defenses, from populations of phages, innumerable antibodies, beneficial polysaccharides, etc., etc., all working together.  Instead of external treatment, there are various ways to increase the natural function of this system: things like spicy food, capsacin, pepper, sad movies featuring orphaned puppies, etc. Anything that will induce a tears and mucus production. 



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## Jonathan Cline
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