Re: [DIYbio] Safety of the RNA Corona Vaccine

Thank you for your contributions. I think the matter is complex and is an example that we should be quite humble towards the complexities in our bodies. As I understand the studies, it is not conclusively clear whether the adjuvants in Pandemrix did not contribute to provoking the occurrence of narcolepsy in the respective patients.
Even mechanisms of action that initially appear simple and safe, such as the new mRNA vaccine, can potentially harbor risks that we cannot assess at the present time. But this is only my opinion and of course I have no proof and of course I hope that everything goes well. But it is part of scientific thinking to be skeptical and to expect things that are not obvious at first sight in my humble opinion.

Jonathan Street schrieb am Samstag, 19. Dezember 2020 um 13:18:56 UTC+1:
The internet archive is great but you do miss any updates. The current url is: https://med.stanford.edu/news/all-news/2011/08/study-draws-connection-between-narcolepsy-and-influenza.html

Not true for many news services but Stanford, and Emmanuel Mignot, do seem to care about communicating retractions. Take https://med.stanford.edu/news/all-news/2013/12/h1n1-triggered-narcolepsy-may-stem-from-molecular-mimicry-study-finds.html as an example.

Link to the article itself: https://pubmed.ncbi.nlm.nih.gov/21866560/

Also, the narcolepsy you're talking about seemed to be caused by the virus, not the vaccine, as later research suggested.
The article would seem to suggest that narcolepsy is caused by the virus and some, but not all, vaccines. The claim was that the Pandemrix vaccine causes narcolepsy, possibly due to specific adjuvants used. Neither the Pandemrix vaccine nor the suspected adjuvants were apparently included in the vaccines used in China where this study was conducted.

It looks like the narcolepsy rate was ~1 in 16,000. This is 6.25 per 100,000. From https://en.wikipedia.org/wiki/Narcolepsy#Epidemiology rates appear to vary substantially:

0.2 in Israel
6.25
50 in USA
600 in Japan

I'm not going to investigate further but if I had a family history of narcolepsy I would probably want to know which adjuvants are used in each vaccine. Fortunately we should soon have multiple vaccines available.

On Fri, 18 Dec 2020 at 04:31, safrazine <capgras.ph...@gmail.com> wrote:
Thanks, Hans, I haven't heard anyone say it better than you did! I wish everyone could communicate it so simply and clearly!

-Ilan

On Thursday, December 17, 2020 at 6:37:02 PM UTC-5 Hans Wilms wrote:
You either vaccinate and have a nanoparticle get RNA with a single gene of the virus into your cells, or risk pretty much the same thing happening but with an entire copy of the virus RNA genome. Also the dosage isn't controlled with the virus, and you become a lethal weapon against grandma.

Also, the narcolepsy you're talking about seemed to be caused by the virus, not the vaccine, as later research suggested. 

On Thu, Dec 17, 2020 at 6:19 PM 'Mike Petersen' via DIYbio <diy...@googlegroups.com> wrote:
Hello all,
How do you rate the safety of the new Corona vaccines, which are based on the principle of RNA vaccination?
Are there any studies online to read or are they not available to the public?
I wonder if you can realistically assess the risk at this point.
When I think about the Pandemrix vaccine in 2009 during the svine flu, where it was not known until years later that it caused narcolepsy in many cases due to an autoimmune reaction, it shows that one should be careful, especially with regard to the long-term effects.
Isn't there a great potential for autoimmune reactions especially with RNA vaccines? Thank you very much for your answers.

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